J0153 HCPCS code: Injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds)

J0153 is the HCPCS Level II code for injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds). In 2024 Medicare paid an average of $0.39 per service for J0153 across 527,620 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 180 per day on outpatient hospital claims. Medicare volume fell 65% from 2022 to 2024 (1,492,078 to 527,620 services). In 2024, about 504 clinicians billed Medicare for J0153 for 10,719 beneficiaries; California, Florida, New York accounted for 63% of services.

Code details

FieldValue
SectionJ codes — Drugs administered other than oral method
Coverage codeD — Special coverage instructions apply
Pricing indicator51 — Drug or biological (priced per ASP/average sales price rules)
BETOS categoryO1E — Other drugs
Added2015-01-01
Last action effective2015-01-01

Who bills J0153 (2024)

MeasureValue
Clinicians billing (by place of service)504
Medicare beneficiaries10,719
States with claims24
Share of services in top 3 states (California, Florida, New York)63%

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J0153, 2022–2024

YearServicesBeneficiariesAvg. allowedAvg. paid
20221,492,07831,472$0.47$0.37
20231,048,62222,307$0.51$0.40
2024527,62010,719$0.50$0.39

States with the most J0153 services (2024)

StateServicesAvg. paid
California144,314$0.40
Florida134,130$0.41
New York53,282$0.39
Texas31,478$0.39
Oklahoma24,010$0.39

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
outpatient hospital claims180Prescribing Information
practitioner claims180Prescribing Information

Medicare policy articles for this code

Covered diagnoses (3,915 ICD-10-CM codes)

The diagnoses most often listed as covered in the policy articles above:

ICD-10-CMDiagnosisArticles listing it
I20.1Angina pectoris with documented spasm6
I20.81Angina pectoris with coronary microvascular dysfunction6
I20.89Other forms of angina pectoris6
I21.01ST elevation (STEMI) myocardial infarction involving left main coronary artery6
I21.02ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery6
I21.09ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wall6
I21.11ST elevation (STEMI) myocardial infarction involving right coronary artery6
I21.19ST elevation (STEMI) myocardial infarction involving other coronary artery of inferior wall6
I21.21ST elevation (STEMI) myocardial infarction involving left circumflex coronary artery6
I21.29ST elevation (STEMI) myocardial infarction involving other sites6

Showing 10 of 3,915. The full list, non-covered diagnoses and CSV export are in Caduvo.

What changed for J0153

Frequently asked questions

What is HCPCS code J0153?

J0153 is the HCPCS Level II code for injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds). Short descriptor: "Adenosine inj 1mg".

How much does Medicare pay for J0153?

In 2024, the average Medicare payment was $0.39 per service (average allowed $0.50).

Does Medicare cover J0153?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

Which diagnoses support coverage for J0153?

Medicare policy articles that cite J0153 list 3,915 covered ICD-10-CM diagnosis codes across 9 articles. The most cited include I20.1 (Angina pectoris with documented spasm), I20.81 (Angina pectoris with coronary microvascular dysfunction), I20.89 (Other forms of angina pectoris). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.

How many units of J0153 can be billed per day?

180 on outpatient hospital claims; 180 on practitioner claims (NCCI medically unlikely edits).

Related J01 codes

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Next steps

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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