J0153 HCPCS code: Injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds)
J0153 is the HCPCS Level II code for injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds). In 2024 Medicare paid an average of $0.39 per service for J0153 across 527,620 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 180 per day on outpatient hospital claims. Medicare volume fell 65% from 2022 to 2024 (1,492,078 to 527,620 services). In 2024, about 504 clinicians billed Medicare for J0153 for 10,719 beneficiaries; California, Florida, New York accounted for 63% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2015-01-01 |
| Last action effective | 2015-01-01 |
Who bills J0153 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 504 |
| Medicare beneficiaries | 10,719 |
| States with claims | 24 |
| Share of services in top 3 states (California, Florida, New York) | 63% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J0153, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 1,492,078 | 31,472 | $0.47 | $0.37 |
| 2023 | 1,048,622 | 22,307 | $0.51 | $0.40 |
| 2024 | 527,620 | 10,719 | $0.50 | $0.39 |
States with the most J0153 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 144,314 | $0.40 |
| Florida | 134,130 | $0.41 |
| New York | 53,282 | $0.39 |
| Texas | 31,478 | $0.39 |
| Oklahoma | 24,010 | $0.39 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 180 | Prescribing Information |
| practitioner claims | 180 | Prescribing Information |
Medicare policy articles for this code
- A54768: Billing and Coding: Cardiac Blood Pool Imaging (Multiple Gated Acquisition Scanning- MUGA, Ventriculography) When Performed in Conjunction with Cardiotoxic Chemotherapy (Palmetto GBA (MAC - Part A, MAC - Part B))
- A56476: Billing and Coding: Cardiac Radionuclide Imaging (Palmetto GBA (MAC - Part A, MAC - Part B))
- A56476: Billing and Coding: Cardiac Radionuclide Imaging (Palmetto GBA (MAC - Part A, MAC - Part B))
- A56494: Billing and Coding: Cardiovascular Nuclear Medicine (CGS Administrators, LLC (MAC - Part A, MAC - Part B))
- A56625: Billing and Coding: Echocardiography (Palmetto GBA (MAC - Part A, MAC - Part B))
- A56625: Billing and Coding: Echocardiography (Palmetto GBA (MAC - Part A, MAC - Part B))
- A56781: Billing and Coding: Transthoracic Echocardiography (TTE) (Wellpoint Federal (MAC - Part A, MAC - Part B))
- A57183: Billing and Coding: Cardiovascular Stress Testing, Including Exercise and/or Pharmacological Stress and Stress Echocardiography (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B))
- A57306: Billing and Coding: Transthoracic Echocardiography (TTE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B))
Covered diagnoses (3,915 ICD-10-CM codes)
The diagnoses most often listed as covered in the policy articles above:
| ICD-10-CM | Diagnosis | Articles listing it |
|---|---|---|
| I20.1 | Angina pectoris with documented spasm | 6 |
| I20.81 | Angina pectoris with coronary microvascular dysfunction | 6 |
| I20.89 | Other forms of angina pectoris | 6 |
| I21.01 | ST elevation (STEMI) myocardial infarction involving left main coronary artery | 6 |
| I21.02 | ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery | 6 |
| I21.09 | ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wall | 6 |
| I21.11 | ST elevation (STEMI) myocardial infarction involving right coronary artery | 6 |
| I21.19 | ST elevation (STEMI) myocardial infarction involving other coronary artery of inferior wall | 6 |
| I21.21 | ST elevation (STEMI) myocardial infarction involving left circumflex coronary artery | 6 |
| I21.29 | ST elevation (STEMI) myocardial infarction involving other sites | 6 |
Showing 10 of 3,915. The full list, non-covered diagnoses and CSV export are in Caduvo.
What changed for J0153
- 2015-01-01: J0153 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J0153?
J0153 is the HCPCS Level II code for injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds). Short descriptor: "Adenosine inj 1mg".
How much does Medicare pay for J0153?
In 2024, the average Medicare payment was $0.39 per service (average allowed $0.50).
Does Medicare cover J0153?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Which diagnoses support coverage for J0153?
Medicare policy articles that cite J0153 list 3,915 covered ICD-10-CM diagnosis codes across 9 articles. The most cited include I20.1 (Angina pectoris with documented spasm), I20.81 (Angina pectoris with coronary microvascular dysfunction), I20.89 (Other forms of angina pectoris). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.
How many units of J0153 can be billed per day?
180 on outpatient hospital claims; 180 on practitioner claims (NCCI medically unlikely edits).
Related J01 codes
- J0120 — Injection, tetracycline, up to 250 mg
- J0121 — Injection, omadacycline, 1 mg
- J0122 — Injection, eravacycline, 1 mg
- J0129 — Injection, abatacept, 10 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
- J0130 — Injection abciximab, 10 mg
- J0131 — Injection, acetaminophen, not otherwise specified,10 mg
- J0132 — Injection, acetylcysteine, 100 mg
- J0133 — Injection, acyclovir, 5 mg
- J0134 — Injection, acetaminophen (fresenius kabi), not therapeutically equivalent to j0131, 10 mg
- J0135 — Injection, adalimumab, 20 mg
- J0136 — Injection, acetaminophen (b braun), not therapeutically equivalent to j0131, 10 mg
- J0137 — Injection, acetaminophen (hikma), not therapeutically equivalent to j0131, 10 mg
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under J0153
- Watch J0153 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J0153
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.