E28.310: Symptomatic premature menopause
E28.310, symptomatic premature menopause, is listed as a covered diagnosis in 3 Medicare billing and coding articles that apply to 2 HCPCS Level II codes, including G0130 (Single energy x-ray absorptiometry (sexa) bone density…), J1740 (Injection, ibandronate sodium, 1 mg). The articles come from 3 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with E28.310 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| G0130 | Single energy x-ray absorptiometry (sexa) bone density study, one or more sites; appendicular skeleton (peripheral) (e.g., radius, wrist, heel) | Special coverage instructions apply | — | 2 |
| J1740 | Injection, ibandronate sodium, 1 mg | Carrier judgment | — | 1 |
Medicare policy articles listing E28.310
- A52421: Billing and Coding: Ibandronate Sodium (Wellpoint Federal (MAC - Part A, MAC - Part B); 1 Level II codes)
- A59040: Billing and Coding: Bone Mass Measurement (Palmetto GBA (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L36460, L39268
- A57132: Billing and Coding: Bone Mass Measurement (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L36460, L39268
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Other E28 diagnoses (Ovarian dysfunction)
- E28.319 — Asymptomatic premature menopause
Frequently asked questions
Does Medicare cover E28.310 (Symptomatic premature menopause)?
Medicare covers items and services, not diagnoses. 3 Medicare billing and coding articles list E28.310 as a covered diagnosis for 2 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 E28.310?
The Level II codes from the policies most specific to this diagnosis are G0130 (Single energy x-ray absorptiometry (sexa) bone density…, 2 articles); J1740 (Injection, ibandronate sodium, 1 mg, 1 article). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list E28.310?
A52421 (Billing and Coding: Ibandronate Sodium); A59040 (Billing and Coding: Bone Mass Measurement); A57132 (Billing and Coding: Bone Mass Measurement).
What is ICD-10-CM code E28.310?
E28.310 is the ICD-10-CM code for symptomatic premature menopause, in category E28 (Ovarian dysfunction), chapter 4: Endocrine, nutritional and metabolic diseases.
Next steps
- Run a reimbursement report for a device billed under G0130
- Watch G0130 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for G0130
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.
Chapter 4: Endocrine, nutritional and metabolic diseases · All diagnoses · HCPCS lookup