E75.241: Niemann-Pick disease type B
E75.241, niemann-Pick disease type B, is listed as a covered diagnosis in 5 Medicare billing and coding articles that apply to 1 HCPCS Level II code, including G0127 (Trimming of dystrophic nails, any number). The articles come from 5 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with E75.241 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| G0127 | Trimming of dystrophic nails, any number | Special coverage instructions apply | — | 5 |
Medicare policy articles listing E75.241
- A57759: Billing and Coding: Routine Foot Care and Debridement of Nails (Wellpoint Federal (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33636, L34246
- A57193: Billing and Coding: Routine Foot Care and Debridement of Nails (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33636, L34246
- A52996: Billing and Coding: Routine Foot Care (Novitas Solutions, Inc. (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
- A56232: Billing and Coding: Foot Care (WPS Insurance Corporation (MAC - Part A, MAC - Part B); 1 Level II codes)
- A57188: Billing and Coding: Routine Foot Care (First Coast Service Options, Inc. (MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Other E75 diagnoses (Disorders of sphingolipid metabolism and other lipid storage disorders)
- E75.240 — Niemann-Pick disease type A
- E75.242 — Niemann-Pick disease type C
- E75.243 — Niemann-Pick disease type D
- E75.244 — Niemann-Pick disease type A/B
- E75.248 — Other Niemann-Pick disease
- E75.249 — Niemann-Pick disease, unspecified
- E75.21 — Fabry (-Anderson) disease
- E75.22 — Gaucher disease
- E75.27 — Pelizaeus-Merzbacher disease
- E75.28 — Canavan disease
- E75.3 — Sphingolipidosis, unspecified
Frequently asked questions
Does Medicare cover E75.241 (Niemann-Pick disease type B)?
Medicare covers items and services, not diagnoses. 5 Medicare billing and coding articles list E75.241 as a covered diagnosis for 1 HCPCS Level II code: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 E75.241?
The Level II codes from the policies most specific to this diagnosis are G0127 (Trimming of dystrophic nails, any number, 5 articles). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list E75.241?
A57759 (Billing and Coding: Routine Foot Care and Debridement of Nails); A57193 (Billing and Coding: Routine Foot Care and Debridement of Nails); A52996 (Billing and Coding: Routine Foot Care), and 2 more articles.
What is ICD-10-CM code E75.241?
E75.241 is the ICD-10-CM code for niemann-Pick disease type B, in category E75 (Disorders of sphingolipid metabolism and other lipid storage disorders), chapter 4: Endocrine, nutritional and metabolic diseases.
Next steps
- Run a reimbursement report for a device billed under G0127
- Watch G0127 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for G0127
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.
Chapter 4: Endocrine, nutritional and metabolic diseases · All diagnoses · HCPCS lookup