G36.0: Neuromyelitis optica [Devic]

G36.0, neuromyelitis optica [Devic], is listed as a covered diagnosis in 15 Medicare billing and coding articles that apply to 45 HCPCS Level II codes, including J9312 (Injection, rituximab, 10 mg), Q5119 (Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mg), Q5115 (Injection, rituximab-abbs, biosimilar, (truxima), 10 mg). The articles come from 7 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with G36.0 as a covered diagnosis

CodeDescriptionMedicare coverageDMEPOS fee 2026 (state range)Articles listing it
J9312Injection, rituximab, 10 mgSpecial coverage instructions apply—4
Q5119Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mgCarrier judgment—4
Q5115Injection, rituximab-abbs, biosimilar, (truxima), 10 mgSpecial coverage instructions apply—4
J1299Injection, eculizumab, 2 mgCarrier judgment—1
Q5151Injection, eculizumab-aagh (epysqli), biosimilar, 2 mgCarrier judgment—1
Q5152Injection, eculizumab-aeeb (bkemv), biosimilar, 2 mgCarrier judgment—1
J1559Injection, immune globulin (hizentra), 100 mgCarrier judgment—2
J1555Injection, immune globulin (cuvitru), 100 mgCarrier judgment—2
J1575Injection, immune globulin/hyaluronidase, (hyqvia), 100 mg immuneglobulinCarrier judgment—2
J1558Injection, immune globulin (xembify), 100 mgCarrier judgment—2
J1569Injection, immune globulin, (gammagard liquid/gammagard liquid erc), 500 mgSpecial coverage instructions apply—2
J1561Injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—2
J1551Injection, immune globulin (cutaquig), 100 mgCarrier judgment—2
J1459Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—2
J1576Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—2
J1557Injection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—2
J1556Injection, immune globulin (bivigam), 500 mgCarrier judgment—2
J1568Injection, immune globulin, (octagam), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—2
J1566Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mgSpecial coverage instructions apply—2
J1554Injection, immune globulin (asceniv), 500 mgCarrier judgment—2
J1572Injection, immune globulin, (flebogamma/flebogamma dif), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—2
J1552Injection, immune globulin (alyglo), 500 mgCarrier judgment—2
J1553Injection, immune globulin (yimmugo), 100 mgCarrier judgment—2
J1577Injection, immune globulin (qivigy), 100 mgCarrier judgment—2
Q5123Injection, rituximab-arrx, biosimilar, (riabni), 10 mgCarrier judgment—3

20 more codes are listed. See every code with payment by region in Caduvo.

Medicare policy articles listing G36.0

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Other G36 diagnoses (Other acute disseminated demyelination)

Frequently asked questions

Does Medicare cover G36.0 (Neuromyelitis optica [Devic])?

Medicare covers items and services, not diagnoses. 15 Medicare billing and coding articles list G36.0 as a covered diagnosis for 45 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 G36.0?

The Level II codes from the policies most specific to this diagnosis are J9312 (Injection, rituximab, 10 mg, 4 articles); Q5119 (Injection, rituximab-pvvr, biosimilar, (ruxience), 10 mg, 4 articles); Q5115 (Injection, rituximab-abbs, biosimilar, (truxima), 10 mg, 4 articles); J1299 (Injection, eculizumab, 2 mg, 1 article); Q5151 (Injection, eculizumab-aagh (epysqli), biosimilar, 2 mg, 1 article). Code choice depends on the item supplied; check each code's descriptor.

Which Medicare policy articles list G36.0?

A54548 (Billing and Coding: Eculizumab, and Biosimilars: EPYSQLI®-eculizumab-aagh, and BKEMV™-eculizumab-aeeb); A58582 (Billing and Coding: Off-label Use of Rituximab and Rituximab Biosimilars); A56786 (Billing and Coding: Immune Globulin), and 12 more articles.

What is ICD-10-CM code G36.0?

G36.0 is the ICD-10-CM code for neuromyelitis optica [Devic], in category G36 (Other acute disseminated demyelination), chapter 6: Diseases of the nervous system.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 6: Diseases of the nervous system · All diagnoses · HCPCS lookup