R41.0: Disorientation, unspecified

R41.0, disorientation, unspecified, is listed as a covered diagnosis in 9 Medicare billing and coding articles that apply to 36 HCPCS Level II codes, including G0480 (Drug test(s), definitive, utilizing (1) drug…), G0483 (Drug test(s), definitive, utilizing (1) drug…), G0482 (Drug test(s), definitive, utilizing (1) drug…). The articles come from 5 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with R41.0 as a covered diagnosis

CodeDescriptionMedicare coverageDMEPOS fee 2026 (state range)Articles listing it
G0480Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 1-7 drug class(es), including metabolite(s) if performedCarrier judgment—4
G0483Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 22 or more drug class(es), including metabolite(s) if performedCarrier judgment—4
G0482Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 15-21 drug class(es), including metabolite(s) if performedCarrier judgment—4
G0481Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem and excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performedCarrier judgment—4
G0659Drug test(s), definitive, utilizing drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem), excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase), performed without method or drug-specific calibration, without matrix-matched quality control material, or without use of stable isotope or other universally recognized internal standard(s) for each drug, drug metabolite or drug class per specimen; qualitative or quantitative, all sources, includes specimen validity testing, per day, any number of drug classesCarrier judgment—4
G0451Development testing, with interpretation and report, per standardized instrument formCarrier judgment—3
C8900Magnetic resonance angiography with contrast, abdomenSpecial coverage instructions apply—1
C8901Magnetic resonance angiography without contrast, abdomenSpecial coverage instructions apply—1
C8902Magnetic resonance angiography without contrast followed by with contrast, abdomenSpecial coverage instructions apply—1
C8909Magnetic resonance angiography with contrast, chest (excluding myocardium)Special coverage instructions apply—1
C8910Magnetic resonance angiography without contrast, chest (excluding myocardium)Special coverage instructions apply—1
C8911Magnetic resonance angiography without contrast followed by with contrast, chest (excluding myocardium)Special coverage instructions apply—1
C8912Magnetic resonance angiography with contrast, lower extremitySpecial coverage instructions apply—1
C8913Magnetic resonance angiography without contrast, lower extremitySpecial coverage instructions apply—1
C8914Magnetic resonance angiography without contrast followed by with contrast, lower extremitySpecial coverage instructions apply—1
C8918Magnetic resonance angiography with contrast, pelvisSpecial coverage instructions apply—1
C8919Magnetic resonance angiography without contrast, pelvisSpecial coverage instructions apply—1
C8920Magnetic resonance angiography without contrast followed by with contrast, pelvisSpecial coverage instructions apply—1
C8931Magnetic resonance angiography with contrast, spinal canal and contentsSpecial coverage instructions apply—1
C8932Magnetic resonance angiography without contrast, spinal canal and contentsSpecial coverage instructions apply—1
C8933Magnetic resonance angiography without contrast followed by with contrast, spinal canal and contentsSpecial coverage instructions apply—1
C8934Magnetic resonance angiography with contrast, upper extremitySpecial coverage instructions apply—1
C8935Magnetic resonance angiography without contrast, upper extremitySpecial coverage instructions apply—1
C8936Magnetic resonance angiography without contrast followed by with contrast, upper extremitySpecial coverage instructions apply—1
G0017Psychotherapy for crisis furnished in an applicable site of service (any place of service at which the non-facility rate for psychotherapy for crisis services applies, other than the office setting); first 60 minutesCarrier judgment—1

11 more codes are listed. See every code with payment by region in Caduvo.

Medicare policy articles listing R41.0

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Other R41 diagnoses (Other symptoms and signs involving cognitive functions and awareness)

Frequently asked questions

Does Medicare cover R41.0 (Disorientation, unspecified)?

Medicare covers items and services, not diagnoses. 9 Medicare billing and coding articles list R41.0 as a covered diagnosis for 36 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 R41.0?

The Level II codes from the policies most specific to this diagnosis are G0480 (Drug test(s), definitive, utilizing (1) drug…, 4 articles); G0483 (Drug test(s), definitive, utilizing (1) drug…, 4 articles); G0482 (Drug test(s), definitive, utilizing (1) drug…, 4 articles); G0481 (Drug test(s), definitive, utilizing (1) drug…, 4 articles); G0659 (Drug test(s), definitive, utilizing drug identification…, 4 articles). Code choice depends on the item supplied; check each code's descriptor.

Which Medicare policy articles list R41.0?

A56915 (Billing and Coding: Urine Drug Testing); A59416 (Billing and Coding: Urine Drug Testing); A54799 (Billing and Coding: Urine Drug Testing), and 6 more articles.

What is ICD-10-CM code R41.0?

R41.0 is the ICD-10-CM code for disorientation, unspecified, in category R41 (Other symptoms and signs involving cognitive functions and awareness), chapter 18: Symptoms, signs and abnormal findings.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 18: Symptoms, signs and abnormal findings · All diagnoses · HCPCS lookup