E2506 HCPCS code: Speech generating device, digitized speech, using pre-recorded messages, greater than 40 minutes recording time

E2506 is the HCPCS Level II code for speech generating device, digitized speech, using pre-recorded messages, greater than 40 minutes recording time. The 2026 Medicare DMEPOS fee schedule pays $3,296.27 to $3,955.55 (NU, new equipment, purchased) depending on the state. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 1 per day on DME suppliers. Its average fee ranks 4 of 7 E25 codes billed NU (family range $559.40–$9,682.09).

Code details

FieldValue
SectionE codes — Durable medical equipment
Coverage codeD — Special coverage instructions apply
Pricing indicator32 — DMEPOS: inexpensive or routinely purchased item
BETOS categoryD1E — Other durable medical equipment
Added2004-01-01
Last action effective2019-01-01

2026 Medicare DMEPOS fee schedule for E2506

ModifierMeaningLowest state feeHighest state feeCeilingFloor
NUnew equipment, purchased$3,296.27$3,955.55$3,296.27$2,801.83
RRrental (monthly)$329.61$395.58$329.61$280.17
UEused equipment, purchased$2,472.16$2,966.65$2,472.16$2,101.34
StateModifierFeeRural fee
AKNU$3,296.27—
ALNU$3,296.27—
ARNU$3,296.27—
AZNU$3,296.27—
CANU$3,296.27—
CONU$3,296.27—
CTNU$3,296.27—
DCNU$3,296.27—
DENU$3,296.27—
FLNU$3,296.27—
GANU$3,296.27—
HINU$3,296.27—
IANU$3,296.27—
IDNU$3,296.27—
ILNU$3,296.27—
INNU$3,296.27—
KSNU$3,296.27—
KYNU$3,296.27—
LANU$3,296.27—
MANU$3,296.27—
MDNU$3,296.27—
MENU$3,296.27—
MINU$3,296.27—
MNNU$3,296.27—
MONU$3,296.27—
MSNU$3,296.27—
MTNU$3,296.27—
NCNU$3,296.27—
NDNU$3,296.27—
NENU$3,296.27—
NHNU$3,296.27—
NJNU$3,296.27—
NMNU$3,296.27—
NVNU$3,296.27—
NYNU$3,296.27—
OHNU$3,296.27—
OKNU$3,296.27—
ORNU$3,296.27—
PANU$3,296.27—
PRNU$3,955.55—
RINU$3,296.27—
SCNU$3,296.27—
SDNU$3,296.27—
TNNU$3,296.27—
TXNU$3,296.27—
UTNU$3,296.27—
VANU$3,296.27—
VINU$3,296.27—
VTNU$3,296.27—
WANU$3,296.27—
WINU$3,296.27—
WVNU$3,296.27—
WYNU$3,296.27—
AKRR$329.61—
ALRR$329.61—
ARRR$329.61—
AZRR$329.61—
CARR$329.61—
CORR$329.61—
CTRR$329.61—
DCRR$329.61—
DERR$329.61—
FLRR$329.61—
GARR$329.61—
HIRR$329.61—
IARR$329.61—
IDRR$329.61—
ILRR$329.61—
INRR$329.61—
KSRR$329.61—
KYRR$329.61—
LARR$329.61—
MARR$329.61—
MDRR$329.61—
MERR$329.61—
MIRR$329.61—
MNRR$329.61—
MORR$329.61—
MSRR$329.61—
MTRR$329.61—
NCRR$329.61—
NDRR$329.61—
NERR$329.61—
NHRR$329.61—
NJRR$329.61—
NMRR$329.61—
NVRR$329.61—
NYRR$329.61—
OHRR$329.61—
OKRR$329.61—
ORRR$329.61—
PARR$329.61—
PRRR$395.58—
RIRR$329.61—
SCRR$329.61—
SDRR$329.61—
TNRR$329.61—
TXRR$329.61—
UTRR$329.61—
VARR$329.61—
VIRR$329.61—
VTRR$329.61—
WARR$329.61—
WIRR$329.61—
WVRR$329.61—
WYRR$329.61—
AKUE$2,472.16—
ALUE$2,472.16—
ARUE$2,472.16—
AZUE$2,472.16—
CAUE$2,472.16—
COUE$2,472.16—
CTUE$2,472.16—
DCUE$2,472.16—
DEUE$2,472.16—
FLUE$2,472.16—
GAUE$2,472.16—
HIUE$2,472.16—
IAUE$2,472.16—
IDUE$2,472.16—
ILUE$2,472.16—
INUE$2,472.16—
KSUE$2,472.16—
KYUE$2,472.16—
LAUE$2,472.16—
MAUE$2,472.16—
MDUE$2,472.16—
MEUE$2,472.16—
MIUE$2,472.16—
MNUE$2,472.16—
MOUE$2,472.16—
MSUE$2,472.16—
MTUE$2,472.16—
NCUE$2,472.16—
NDUE$2,472.16—
NEUE$2,472.16—
NHUE$2,472.16—
NJUE$2,472.16—
NMUE$2,472.16—
NVUE$2,472.16—
NYUE$2,472.16—
OHUE$2,472.16—
OKUE$2,472.16—
ORUE$2,472.16—
PAUE$2,472.16—
PRUE$2,966.65—
RIUE$2,472.16—
SCUE$2,472.16—
SDUE$2,472.16—
TNUE$2,472.16—
TXUE$2,472.16—
UTUE$2,472.16—
VAUE$2,472.16—
VIUE$2,472.16—
VTUE$2,472.16—
WAUE$2,472.16—
WIUE$2,472.16—
WVUE$2,472.16—
WYUE$2,472.16—

How the E2506 fee compares

MeasureValue
Rank among 7 E25 codes billed NU (lowest = 1)4
Family fee range (average of state fees)$559.40–$9,682.09
Rural fee uplift—

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
DME suppliers1Code Descriptor / CPT Instruction

Medicare policy articles for this code

What changed for E2506

Frequently asked questions

What is HCPCS code E2506?

E2506 is the HCPCS Level II code for speech generating device, digitized speech, using pre-recorded messages, greater than 40 minutes recording time. Short descriptor: "Sgd prerec msg > 40 min".

How much does Medicare pay for E2506?

Under the 2026 DMEPOS fee schedule, non-rural state fees are NU (new equipment, purchased): $3,296.27–$3,955.55; RR (rental (monthly)): $329.61–$395.58; UE (used equipment, purchased): $2,472.16–$2,966.65. Rural fees can be higher.

Does Medicare cover E2506?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

Did the Medicare fee for E2506 change in 2026?

The average non-rural state fee for NU moved from $3,243.84 in 2025 to $3,308.71 in 2026 (+2.0%). CMS's next quarterly HCPCS and DMEPOS update takes effect January 1, 2027.

How many units of E2506 can be billed per day?

1 on DME suppliers (NCCI medically unlikely edits).

Related E25 codes

Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.

Next steps

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule 2026; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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