J0289 HCPCS code: Injection, amphotericin b liposome, 10 mg
J0289 is the HCPCS Level II code for injection, amphotericin b liposome, 10 mg. In 2024 Medicare paid an average of $19.62 per service for J0289 across 3,072 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 150 per day on DME suppliers. Medicare volume fell 6% from 2022 to 2024 (3,261 to 3,072 services). In 2024, 36 suppliers billed Medicare for J0289 (purchases), serving 39 beneficiaries; Washington, California, Texas accounted for 61% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2003-01-01 |
| Last action effective | 2003-01-01 |
Who bills J0289 (2024)
| Measure | Value |
|---|---|
| Suppliers billing rentals | — |
| Suppliers billing purchases | 36 |
| Referring clinicians | 48 |
| Medicare beneficiaries | 39 |
| States with claims | 7 |
| Share of services in top 3 states (Washington, California, Texas) | 61% |
| Year | Suppliers | Beneficiaries |
|---|---|---|
| 2022 | 30 | 33 |
| 2023 | 29 | 35 |
| 2024 | 36 | 39 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J0289, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 3,261 | 18 | $27.51 | $21.97 |
| 2023 | 2,974 | 12 | $26.89 | $21.36 |
| 2024 | 3,072 | 14 | $24.63 | $19.62 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| DME suppliers | 150 | Clinical: CMS Workgroup |
| outpatient hospital claims | 115 | Prescribing Information |
| practitioner claims | 50 | Clinical: Data |
What changed for J0289
- 2003-01-01: J0289 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J0289?
J0289 is the HCPCS Level II code for injection, amphotericin b liposome, 10 mg. Short descriptor: "Amphotericin b liposome inj".
How much does Medicare pay for J0289?
In 2024, the average Medicare payment was $19.62 per service (average allowed $24.63).
Does Medicare cover J0289?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J0289 can be billed per day?
150 on DME suppliers; 115 on outpatient hospital claims; 50 on practitioner claims (NCCI medically unlikely edits).
Related J02 codes
- J0200 — Injection, alatrofloxacin mesylate, 100 mg
- J0202 — Injection, alemtuzumab, 1 mg
- J0205 — Injection, alglucerase, per 10 units
- J0206 — Injection, allopurinol sodium, 1 mg
- J0207 — Injection, amifostine, 500 mg
- J0208 — Injection, sodium thiosulfate (pedmark), 100 mg
- J0209 — Injection, sodium thiosulfate (hope), 100 mg
- J0210 — Injection, methyldopate hcl, up to 250 mg
- J0211 — Injection, sodium nitrite 3 mg and sodium thiosulfate 125 mg (nithiodote)
- J0215 — Injection, alefacept, 0.5 mg
- J0216 — Injection, alfentanil hydrochloride, 500 micrograms
- J0217 — Injection, velmanase alfa-tycv, 1 mg
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under J0289
- Watch J0289 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J0289
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.