J0775 HCPCS code: Injection, collagenase, clostridium histolyticum, 0.01 mg
J0775 is the HCPCS Level II code for injection, collagenase, clostridium histolyticum, 0.01 mg. In 2024 Medicare paid an average of $53.97 per service for J0775 across 1,022,640 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. The NCCI unit limit is 180 per day on outpatient hospital claims. Medicare volume fell 4% from 2022 to 2024 (1,069,680 to 1,022,640 services). In 2024, about 1,835 clinicians billed Medicare for J0775 for 5,999 beneficiaries; California, Florida, New York accounted for 32% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2011-01-01 |
| Last action effective | 2011-01-01 |
Who bills J0775 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 1,835 |
| Medicare beneficiaries | 5,999 |
| States with claims | 44 |
| Share of services in top 3 states (California, Florida, New York) | 32% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J0775, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 1,069,680 | 6,658 | $57.13 | $45.54 |
| 2023 | 1,027,305 | 6,250 | $62.80 | $50.50 |
| 2024 | 1,022,640 | 5,999 | $66.66 | $53.97 |
States with the most J0775 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 187,492 | $54.15 |
| Florida | 85,574 | $54.53 |
| New York | 51,774 | $52.78 |
| Texas | 42,164 | $54.09 |
| Illinois | 36,619 | $54.28 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 180 | CMS Policy |
| practitioner claims | 180 | CMS Policy |
What changed for J0775
- 2011-01-01: J0775 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J0775?
J0775 is the HCPCS Level II code for injection, collagenase, clostridium histolyticum, 0.01 mg. Short descriptor: "Collagenase, clost hist inj".
How much does Medicare pay for J0775?
In 2024, the average Medicare payment was $53.97 per service (average allowed $66.66).
Does Medicare cover J0775?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
How many units of J0775 can be billed per day?
180 on outpatient hospital claims; 180 on practitioner claims (NCCI medically unlikely edits).
Related J07 codes
- J0701 — Injection, cefepime hydrochloride (baxter), not therapeutically equivalent to maxipime, 500 mg
- J0702 — Injection, betamethasone acetate 3 mg and betamethasone sodium phosphate 3 mg
- J0703 — Injection, cefepime hydrochloride (b braun), not therapeutically equivalent to maxipime, 500 mg
- J0706 — Injection, caffeine citrate, 5 mg
- J0710 — Injection, cephapirin sodium, up to 1 gm
- J0712 — Injection, ceftaroline fosamil, 10 mg
- J0713 — Injection, ceftazidime, per 500 mg
- J0714 — Injection, ceftazidime and avibactam, 0.5 g/0.125 g
- J0715 — Injection, ceftizoxime sodium, per 500 mg
- J0716 — Injection, centruroides immune f(ab)2, up to 120 milligrams
- J0717 — Injection, certolizumab pegol, 1 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)
- J0720 — Injection, chloramphenicol sodium succinate, up to 1 gm
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Next steps
- Run a reimbursement report for a device billed under J0775
- Watch J0775 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J0775
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.