J0878 HCPCS code: Injection, daptomycin, 1 mg
J0878 is the HCPCS Level II code for injection, daptomycin, 1 mg. In 2024 Medicare paid an average of $0.04 per service for J0878 across 36,229,521 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. The NCCI unit limit is 1000 per day on DME suppliers. Medicare volume fell 22% from 2022 to 2024 (46,224,614 to 36,229,521 services). In 2024, about 956 clinicians billed Medicare for J0878 for 3,503 beneficiaries; Florida, Georgia, Texas accounted for 58% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2005-01-01 |
| Last action effective | 2024-01-01 |
Who bills J0878 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 956 |
| Medicare beneficiaries | 3,503 |
| States with claims | 29 |
| Share of services in top 3 states (Florida, Georgia, Texas) | 58% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J0878, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 46,224,614 | 4,301 | $0.05 | $0.04 |
| 2023 | 44,462,868 | 4,023 | $0.05 | $0.04 |
| 2024 | 36,229,521 | 3,503 | $0.05 | $0.04 |
States with the most J0878 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Florida | 12,336,530 | $0.04 |
| Georgia | 4,567,358 | $0.04 |
| Texas | 3,722,325 | $0.04 |
| Colorado | 3,017,039 | $0.04 |
| Michigan | 1,642,181 | $0.04 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| DME suppliers | 1000 | CMS Policy |
| outpatient hospital claims | 1000 | CMS Policy |
| practitioner claims | 1000 | CMS Policy |
What changed for J0878
- 2005-01-01: J0878 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J0878?
J0878 is the HCPCS Level II code for injection, daptomycin, 1 mg. Short descriptor: "Daptomycin injection".
How much does Medicare pay for J0878?
In 2024, the average Medicare payment was $0.04 per service (average allowed $0.05).
Does Medicare cover J0878?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
How many units of J0878 can be billed per day?
1000 on DME suppliers; 1000 on outpatient hospital claims; 1000 on practitioner claims (NCCI medically unlikely edits).
Related J08 codes
- J0800 — Injection, corticotropin, up to 40 units
- J0801 — Injection, corticotropin (acthar gel), up to 40 units
- J0802 — Injection, corticotropin (ani), up to 40 units
- J0833 — Injection, cosyntropin, not otherwise specified, 0.25 mg
- J0834 — Injection, cosyntropin, 0.25 mg
- J0840 — Injection, crotalidae polyvalent immune fab (ovine), up to 1 gram
- J0841 — Injection, crotalidae immune f(ab')2 (equine), 120 mg
- J0850 — Injection, cytomegalovirus immune globulin intravenous (human), per vial
- J0870 — Injection, imetelstat, 1 mg
- J0871 — Injection, daptomycin (endo), not therapeutically equivalent to j0878, 1 mg
- J0872 — Injection, daptomycin (xellia), unrefrigerated, not therapeutically equivalent to j0878 or j0873, 1 mg
- J0873 — Injection, daptomycin (xellia), not therapeutically equivalent to j0878 or j0872, 1 mg
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Next steps
- Run a reimbursement report for a device billed under J0878
- Watch J0878 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J0878
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.