J1954 HCPCS code: Injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg

J1954 is the HCPCS Level II code for injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg. In 2024 Medicare paid an average of $236.39 per service for J1954 across 6,638 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. The NCCI unit limit is 3 per day on outpatient hospital claims. Medicare volume rose 151% from 2023 to 2024 (2,642 to 6,638 services). In 2024, about 224 clinicians billed Medicare for J1954 for 796 beneficiaries.

Code details

FieldValue
SectionJ codes — Drugs administered other than oral method
Coverage codeC — Carrier judgment
Pricing indicator51 — Drug or biological (priced per ASP/average sales price rules)
BETOS categoryO1D — Chemotherapy
Added2023-01-01
Last action effective2025-07-01

Who bills J1954 (2024)

MeasureValue
Clinicians billing (by place of service)224
Medicare beneficiaries796
States with claims2

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J1954, 2023–2024

YearServicesBeneficiariesAvg. allowedAvg. paid
20232,642603$379.13$302.07
20246,638796$299.11$236.39

States with the most J1954 services (2024)

StateServicesAvg. paid
Florida5,578$235.68
California988$241.01

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
outpatient hospital claims3Prescribing Information
practitioner claims3Prescribing Information

Medicare policy articles for this code

Covered diagnoses (246 ICD-10-CM codes)

The diagnoses most often listed as covered in the policy articles above:

ICD-10-CMDiagnosisArticles listing it
C08.0Malignant neoplasm of submandibular gland2
C08.1Malignant neoplasm of sublingual gland2
C48.1Malignant neoplasm of specified parts of peritoneum2
C48.8Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum2
C50.011Malignant neoplasm of nipple and areola, right female breast2
C50.012Malignant neoplasm of nipple and areola, left female breast2
C50.021Malignant neoplasm of nipple and areola, right male breast2
C50.022Malignant neoplasm of nipple and areola, left male breast2
C50.111Malignant neoplasm of central portion of right female breast2
C50.112Malignant neoplasm of central portion of left female breast2

Showing 10 of 246. The full list, non-covered diagnoses and CSV export are in Caduvo.

What changed for J1954

Frequently asked questions

What is HCPCS code J1954?

J1954 is the HCPCS Level II code for injection, leuprolide acetate for depot suspension (lutrate depot), 7.5 mg. Short descriptor: "Inj leu acet lutr dpt 7.5 mg".

How much does Medicare pay for J1954?

In 2024, the average Medicare payment was $236.39 per service (average allowed $299.11).

Does Medicare cover J1954?

Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.

Which diagnoses support coverage for J1954?

Medicare policy articles that cite J1954 list 246 covered ICD-10-CM diagnosis codes across 2 articles. The most cited include C08.0 (Malignant neoplasm of submandibular gland), C08.1 (Malignant neoplasm of sublingual gland), C48.1 (Malignant neoplasm of specified parts of peritoneum). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.

How many units of J1954 can be billed per day?

3 on outpatient hospital claims; 3 on practitioner claims (NCCI medically unlikely edits).

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Next steps

Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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