J2510 HCPCS code: Injection, penicillin g procaine, aqueous, up to 600,000 units
J2510 is the HCPCS Level II code for injection, penicillin g procaine, aqueous, up to 600,000 units. In 2023 Medicare paid an average of $28.61 per service for J2510 across 48 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 4 per day on outpatient hospital claims. Medicare volume rose 23% from 2022 to 2023 (39 to 48 services). In 2023, about 12 clinicians billed Medicare for J2510 for 17 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 1982-01-01 |
| Last action effective | 2023-01-01 |
Who bills J2510 (2023)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 12 |
| Medicare beneficiaries | 17 |
| States with claims | 0 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J2510, 2022–2023
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 39 | 16 | $32.36 | $23.51 |
| 2023 | 48 | 17 | $37.49 | $28.61 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 4 | Prescribing Information |
| practitioner claims | 4 | Prescribing Information |
What changed for J2510
- 1982-01-01: J2510 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2510?
J2510 is the HCPCS Level II code for injection, penicillin g procaine, aqueous, up to 600,000 units. Short descriptor: "Penicillin g procaine inj".
How much does Medicare pay for J2510?
In 2023, the average Medicare payment was $28.61 per service (average allowed $37.49).
Does Medicare cover J2510?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J2510 can be billed per day?
4 on outpatient hospital claims; 4 on practitioner claims (NCCI medically unlikely edits).
Related J25 codes
- J2501 — Injection, paricalcitol, 1 mcg
- J2502 — Injection, pasireotide long acting, 1 mg
- J2503 — Injection, pegaptanib sodium, 0.3 mg
- J2504 — Injection, pegademase bovine, 25 iu
- J2505 — Injection, pegfilgrastim, 6 mg
- J2506 — Injection, pegfilgrastim, excludes biosimilar, 0.5 mg
- J2507 — Injection, pegloticase, 1 mg
- J2508 — Injection, pegunigalsidase alfa-iwxj, 1 mg
- J2513 — Injection, pentastarch, 10% solution, 100 ml
- J2515 — Injection, pentobarbital sodium, per 50 mg
- J2516 — Injection, pentamidine isethionate, 1 mg
- J2540 — Injection, penicillin g potassium, up to 600,000 units
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Next steps
- Run a reimbursement report for a device billed under J2510
- Watch J2510 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2510
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.