J2788 HCPCS code: Injection, rho d immune globulin, human, minidose, 50 micrograms (250 i.u.)
J2788 is the HCPCS Level II code for injection, rho d immune globulin, human, minidose, 50 micrograms (250 i.u.). In 2023 Medicare paid an average of $17.95 per service for J2788 across 13 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 1 per day on outpatient hospital claims. Medicare volume rose 8% from 2022 to 2023 (12 to 13 services). In 2023, about 2 clinicians billed Medicare for J2788 for 13 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2003-01-01 |
| Last action effective | 2014-01-01 |
Who bills J2788 (2023)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 2 |
| Medicare beneficiaries | 13 |
| States with claims | 1 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J2788, 2022–2023
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 12 | 12 | $20.70 | $16.54 |
| 2023 | 13 | 13 | $22.54 | $17.95 |
States with the most J2788 services (2023)
| State | Services | Avg. paid |
|---|---|---|
| New York | 12 | $19.45 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 1 | Prescribing Information |
| practitioner claims | 1 | Prescribing Information |
Medicare policy articles for this code
- A57160: Billing and Coding: Immune Thrombocytopenia (ITP) Therapy (CGS Administrators, LLC (MAC - Part A, MAC - Part B))
Covered diagnoses (1 ICD-10-CM codes)
The diagnoses most often listed as covered in the policy articles above:
| ICD-10-CM | Diagnosis | Articles listing it |
|---|---|---|
| D69.3 | Immune thrombocytopenic purpura | 1 |
What changed for J2788
- 2003-01-01: J2788 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2788?
J2788 is the HCPCS Level II code for injection, rho d immune globulin, human, minidose, 50 micrograms (250 i.u.). Short descriptor: "Rho d immune globulin 50 mcg".
How much does Medicare pay for J2788?
In 2023, the average Medicare payment was $17.95 per service (average allowed $22.54).
Does Medicare cover J2788?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Which diagnoses support coverage for J2788?
Medicare policy articles that cite J2788 list 1 covered ICD-10-CM diagnosis codes across 1 article. The most cited include D69.3 (Immune thrombocytopenic purpura). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.
How many units of J2788 can be billed per day?
1 on outpatient hospital claims; 1 on practitioner claims (NCCI medically unlikely edits).
Related J27 codes
- J2700 — Injection, oxacillin sodium, up to 250 mg
- J2704 — Injection, propofol, 10 mg
- J2710 — Injection, neostigmine methylsulfate, up to 0.5 mg
- J2720 — Injection, protamine sulfate, per 10 mg
- J2724 — Injection, protein c concentrate, intravenous, human, 10 iu
- J2725 — Injection, protirelin, per 250 mcg
- J2730 — Injection, pralidoxime chloride, up to 1 gm
- J2760 — Injection, phentolamine mesylate, up to 5 mg
- J2765 — Injection, metoclopramide hcl, up to 10 mg
- J2770 — Injection, quinupristin/dalfopristin, 500 mg (150/350)
- J2777 — Injection, faricimab-svoa, 0.1 mg
- J2778 — Injection, ranibizumab, 0.1 mg
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Next steps
- Run a reimbursement report for a device billed under J2788
- Watch J2788 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2788
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.