J3470 HCPCS code: Injection, hyaluronidase, up to 150 units
J3470 is the HCPCS Level II code for injection, hyaluronidase, up to 150 units. In 2024 Medicare paid an average of $42.83 per service for J3470 across 134 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 3 per day on outpatient hospital claims. Medicare volume fell 8% from 2022 to 2024 (146 to 134 services). In 2024, about 29 clinicians billed Medicare for J3470 for 94 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 1982-01-01 |
| Last action effective | 1997-01-01 |
Who bills J3470 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 29 |
| Medicare beneficiaries | 94 |
| States with claims | 2 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J3470, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 146 | 111 | $54.05 | $43.07 |
| 2023 | 136 | 98 | $55.73 | $43.94 |
| 2024 | 134 | 94 | $54.46 | $42.83 |
States with the most J3470 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 77 | $45.37 |
| Florida | 28 | $41.53 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 3 | Clinical: Data |
| practitioner claims | 3 | Clinical: Data |
What changed for J3470
- 1982-01-01: J3470 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J3470?
J3470 is the HCPCS Level II code for injection, hyaluronidase, up to 150 units. Short descriptor: "Hyaluronidase injection".
How much does Medicare pay for J3470?
In 2024, the average Medicare payment was $42.83 per service (average allowed $54.46).
Does Medicare cover J3470?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J3470 can be billed per day?
3 on outpatient hospital claims; 3 on practitioner claims (NCCI medically unlikely edits).
Related J34 codes
- J3400 — Injection, triflupromazine hcl, up to 20 mg
- J3401 — Beremagene geperpavec-svdt for topical administration, containing nominal 5 x 10^9 pfu/ml vector genomes, per 0.1 ml
- J3402 — Injection, remestemcel-l-rknd, per therapeutic dose
- J3403 — Revakinagene taroretcel-lwey, per implant
- J3410 — Injection, hydroxyzine hcl, up to 25 mg
- J3411 — Injection, thiamine hcl, 100 mg
- J3415 — Injection, pyridoxine hcl, 100 mg
- J3420 — Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg
- J3424 — Injection, hydroxocobalamin, intravenous, 25 mg
- J3425 — Injection, hydroxocobalamin, intramuscular, 10 mcg
- J3430 — Injection, phytonadione (vitamin k), per 1 mg
- J3465 — Injection, voriconazole, 10 mg
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Next steps
- Run a reimbursement report for a device billed under J3470
- Watch J3470 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J3470
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.