J7503 HCPCS code: Tacrolimus, extended release, (envarsus xr), oral, 0.25 mg
J7503 is the HCPCS Level II code for tacrolimus, extended release, (envarsus xr), oral, 0.25 mg. In 2024 Medicare paid an average of $1.35 per service for J7503 across 70,477,400 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 3600 per day on DME suppliers. Medicare volume fell 1% from 2022 to 2024 (71,546,089 to 70,477,400 services). In 2024, 2,688 suppliers billed Medicare for J7503 (purchases), serving 15,946 beneficiaries; Illinois, New York, Missouri accounted for 24% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2016-01-01 |
| Last action effective | 2019-01-01 |
Who bills J7503 (2024)
| Measure | Value |
|---|---|
| Suppliers billing rentals | — |
| Suppliers billing purchases | 2,688 |
| Referring clinicians | 4,553 |
| Medicare beneficiaries | 15,946 |
| States with claims | 52 |
| Share of services in top 3 states (Illinois, New York, Missouri) | 24% |
| Year | Suppliers | Beneficiaries |
|---|---|---|
| 2022 | 2,130 | 14,612 |
| 2023 | 2,402 | 15,469 |
| 2024 | 2,688 | 15,946 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J7503, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 71,546,089 | 14,612 | $1.53 | $1.19 |
| 2023 | 71,592,205 | 15,469 | $1.64 | $1.27 |
| 2024 | 70,477,400 | 15,946 | $1.75 | $1.35 |
States with the most J7503 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Illinois | 6,751,217 | $1.36 |
| New York | 5,478,877 | $1.36 |
| Missouri | 4,720,636 | $1.36 |
| California | 4,611,897 | $1.36 |
| Florida | 4,275,801 | $1.36 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| DME suppliers | 3600 | Prescribing Information |
| outpatient hospital claims | 120 | Prescribing Information |
What changed for J7503
- 2016-01-01: J7503 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J7503?
J7503 is the HCPCS Level II code for tacrolimus, extended release, (envarsus xr), oral, 0.25 mg. Short descriptor: "Tacrol envarsus ex rel oral".
How much does Medicare pay for J7503?
In 2024, the average Medicare payment was $1.35 per service (average allowed $1.75).
Does Medicare cover J7503?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J7503 can be billed per day?
3600 on DME suppliers; 120 on outpatient hospital claims (NCCI medically unlikely edits).
Related J75 codes
- J7500 — Azathioprine, oral, 50 mg
- J7501 — Azathioprine, parenteral, 100 mg
- J7502 — Cyclosporine, oral, 100 mg
- J7504 — Lymphocyte immune globulin, antithymocyte globulin, equine, parenteral, 250 mg
- J7505 — Muromonab-cd3, parenteral, 5 mg
- J7506 — Prednisone, oral, per 5 mg
- J7507 — Tacrolimus, immediate release, oral, 1 mg
- J7508 — Tacrolimus, extended release, (astagraf xl), oral, 0.1 mg
- J7509 — Methylprednisolone oral, per 4 mg
- J7510 — Prednisolone oral, per 5 mg
- J7511 — Lymphocyte immune globulin, antithymocyte globulin, rabbit, parenteral, 25 mg
- J7512 — Prednisone, immediate release or delayed release, oral, 1 mg
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Next steps
- Run a reimbursement report for a device billed under J7503
- Watch J7503 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J7503
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.