J7639 HCPCS code: Dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram

J7639 is the HCPCS Level II code for dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram. In 2024 Medicare paid an average of $41.07 per service for J7639 across 448,884 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 234 per day on DME suppliers. Medicare volume fell 19% from 2022 to 2024 (551,079 to 448,884 services). In 2024, 223 suppliers billed Medicare for J7639 (purchases), serving 901 beneficiaries; California, New York, Florida accounted for 22% of services.

Code details

Who bills J7639 (2024)

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J7639, 2022–2024

States with the most J7639 services (2024)

NCCI unit limits (MUE)

Medicare policy articles for this code

• A52466: Nebulizers - Policy Article (CGS Administrators, LLC (DME MAC) Noridian Healthcare Solutions, LLC (DME MAC)) — mentions this code in its coding guidance

Covered diagnoses (215 ICD-10-CM codes)

The diagnoses most often listed as covered in the policy articles above:

Showing 10 of 215. The full list, non-covered diagnoses and CSV export are in Caduvo.

What changed for J7639

• 2000-01-01: J7639 added to HCPCS Level II
• Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01

Frequently asked questions

What is HCPCS code J7639?

J7639 is the HCPCS Level II code for dornase alfa, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per milligram. Short descriptor: "Dornase alfa non-comp unit".

How much does Medicare pay for J7639?

In 2024, the average Medicare payment was $41.07 per service (average allowed $52.70).

Does Medicare cover J7639?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

Which diagnoses support coverage for J7639?

Medicare policy articles that cite J7639 list 215 covered ICD-10-CM diagnosis codes across 1 article. The most cited include A15.0 (Tuberculosis of lung), A22.1 (Pulmonary anthrax), A37.01 (Whooping cough due to Bordetella pertussis with pneumonia). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.

How many units of J7639 can be billed per day?

234 on DME suppliers; 3 on practitioner claims (NCCI medically unlikely edits).

Related J76 codes

• J7601 — Ensifentrine, inhalation suspension, fda approved final product, non-compounded, administered through dme, unit dose form, 3 mg
• J7604 — Acetylcysteine, inhalation solution, compounded product, administered through dme, unit dose form, per gram
• J7605 — Arformoterol, inhalation solution, fda approved final product, non-compounded, administered through dme, unit dose form, 15 micrograms
• J7606 — Formoterol fumarate, inhalation solution, fda approved final product, non-compounded, administered through dme, unit dose form, 20 micrograms
• J7607 — Levalbuterol, inhalation solution, compounded product, administered through dme, concentrated form, 0.5 mg
• J7608 — Acetylcysteine, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, per gram
• J7609 — Albuterol, inhalation solution, compounded product, administered through dme, unit dose, 1 mg
• J7610 — Albuterol, inhalation solution, compounded product, administered through dme, concentrated form, 1 mg
• J7611 — Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, 1 mg
• J7612 — Levalbuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, 0.5 mg
• J7613 — Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 1 mg
• J7614 — Levalbuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 0.5 mg

Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.

Next steps

• Run a reimbursement report for a device billed under J7639
• Watch J7639 for fee, coverage and descriptor changes
• Build a full Medicare revenue model for J7639

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

All J codes · HCPCS lookup