J9215 HCPCS code: Injection, interferon, alfa-n3, (human leukocyte derived), 250,000 iu
J9215 is the HCPCS Level II code for injection, interferon, alfa-n3, (human leukocyte derived), 250,000 iu. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1D — Chemotherapy |
| Added | 1993-01-01 |
| Last action effective | 2009-01-01 |
Medicare policy articles for this code
- A55639: Billing and Coding: Chemotherapy Agents for Non-Oncologic Conditions (WPS Insurance Corporation (MAC - Part A, MAC - Part B))
Covered diagnoses (564 ICD-10-CM codes)
The diagnoses most often listed as covered in the policy articles above:
| ICD-10-CM | Diagnosis | Articles listing it |
|---|---|---|
| A63.0 | Anogenital (venereal) warts | 1 |
| B07.0 | Plantar wart | 1 |
| B07.8 | Other viral warts | 1 |
| B07.9 | Viral wart, unspecified | 1 |
| B27.00 | Gammaherpesviral mononucleosis without complication | 1 |
| B27.01 | Gammaherpesviral mononucleosis with polyneuropathy | 1 |
| B27.02 | Gammaherpesviral mononucleosis with meningitis | 1 |
| B27.09 | Gammaherpesviral mononucleosis with other complications | 1 |
| D47.3 | Essential (hemorrhagic) thrombocythemia | 1 |
| D47.Z1 | Post-transplant lymphoproliferative disorder (PTLD) | 1 |
Showing 10 of 564. The full list, non-covered diagnoses and CSV export are in Caduvo.
What changed for J9215
- 1993-01-01: J9215 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J9215?
J9215 is the HCPCS Level II code for injection, interferon, alfa-n3, (human leukocyte derived), 250,000 iu. Short descriptor: "Interferon alfa-n3 inj".
Does Medicare cover J9215?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Which diagnoses support coverage for J9215?
Medicare policy articles that cite J9215 list 564 covered ICD-10-CM diagnosis codes across 1 article. The most cited include A63.0 (Anogenital (venereal) warts), B07.0 (Plantar wart), B07.8 (Other viral warts). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.
Related J92 codes
- J9200 — Injection, floxuridine, 500 mg
- J9201 — Injection, gemcitabine hydrochloride, not otherwise specified, 200 mg
- J9202 — Goserelin acetate implant, per 3.6 mg
- J9203 — Injection, gemtuzumab ozogamicin, 0.1 mg
- J9204 — Injection, mogamulizumab-kpkc, 1 mg
- J9205 — Injection, irinotecan liposome, 1 mg
- J9206 — Injection, irinotecan, 20 mg
- J9207 — Injection, ixabepilone, 1 mg
- J9208 — Injection, ifosfamide, 1 gram
- J9209 — Injection, mesna, 200 mg
- J9210 — Injection, emapalumab-lzsg, 1 mg
- J9211 — Injection, idarubicin hydrochloride, 5 mg
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Next steps
- Run a reimbursement report for a device billed under J9215
- Watch J9215 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J9215
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.