J9245 HCPCS code: Injection, melphalan hydrochloride, not otherwise specified, 50 mg

J9245 is the HCPCS Level II code for injection, melphalan hydrochloride, not otherwise specified, 50 mg. In 2024 Medicare paid an average of $123.09 per service for J9245 across 151 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 11 per day on outpatient hospital claims. Medicare volume rose 64% from 2022 to 2024 (92 to 151 services). In 2024, about 21 clinicians billed Medicare for J9245 for 24 beneficiaries.

Code details

FieldValue
SectionJ codes — Drugs administered other than oral method
Coverage codeD — Special coverage instructions apply
Pricing indicator51 — Drug or biological (priced per ASP/average sales price rules)
BETOS categoryO1D — Chemotherapy
Added1995-01-01
Last action effective2020-07-01

Who bills J9245 (2024)

MeasureValue
Clinicians billing (by place of service)21
Medicare beneficiaries24
States with claims0

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J9245, 2022–2024

YearServicesBeneficiariesAvg. allowedAvg. paid
20229214$202.62$161.69
20239713$189.62$151.08
202415124$154.49$123.09

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
outpatient hospital claims11Clinical: Society Comment
practitioner claims9Clinical: Society Comment

What changed for J9245

Frequently asked questions

What is HCPCS code J9245?

J9245 is the HCPCS Level II code for injection, melphalan hydrochloride, not otherwise specified, 50 mg. Short descriptor: "Inj melpha hydroch nos 50 mg".

How much does Medicare pay for J9245?

In 2024, the average Medicare payment was $123.09 per service (average allowed $154.49).

Does Medicare cover J9245?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

How many units of J9245 can be billed per day?

11 on outpatient hospital claims; 9 on practitioner claims (NCCI medically unlikely edits).

Related J92 codes

Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.

Next steps

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

All J codes · HCPCS lookup