J9268 HCPCS code: Injection, pentostatin, 10 mg

J9268 is the HCPCS Level II code for injection, pentostatin, 10 mg. In 2024 Medicare paid an average of $1,902.68 per service for J9268 across 45 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 1 per day on outpatient hospital claims. Medicare volume fell 4% from 2022 to 2024 (47 to 45 services). In 2024, about 23 clinicians billed Medicare for J9268 for 13 beneficiaries.

Code details

FieldValue
SectionJ codes — Drugs administered other than oral method
Coverage codeD — Special coverage instructions apply
Pricing indicator51 — Drug or biological (priced per ASP/average sales price rules)
BETOS categoryO1D — Chemotherapy
Added1994-01-01
Last action effective2009-01-01

Who bills J9268 (2024)

MeasureValue
Clinicians billing (by place of service)23
Medicare beneficiaries13
States with claims0

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J9268, 2022–2024

YearServicesBeneficiariesAvg. allowedAvg. paid
20224713$2,071.08$1,645.27
20238812$2,197.51$1,781.71
20244513$2,366.47$1,902.68

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
outpatient hospital claims1Prescribing Information
practitioner claims1Prescribing Information

What changed for J9268

Frequently asked questions

What is HCPCS code J9268?

J9268 is the HCPCS Level II code for injection, pentostatin, 10 mg. Short descriptor: "Pentostatin injection".

How much does Medicare pay for J9268?

In 2024, the average Medicare payment was $1,902.68 per service (average allowed $2,366.47).

Does Medicare cover J9268?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

How many units of J9268 can be billed per day?

1 on outpatient hospital claims; 1 on practitioner claims (NCCI medically unlikely edits).

Related J92 codes

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Next steps

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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