Q9955 HCPCS code: Injection, perflexane lipid microspheres, per ml

Q9955 is the HCPCS Level II code for injection, perflexane lipid microspheres, per ml. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case.

Code details

Medicare policy articles for this code

• A56505: Billing and Coding: Transesophageal Echocardiography (TEE) (Novitas Solutions, Inc. (MAC - Part A, MAC - Part B))
• A56781: Billing and Coding: Transthoracic Echocardiography (TTE) (National Government Services, Inc. (MAC - Part A, MAC - Part B))
• A57306: Billing and Coding: Transthoracic Echocardiography (TTE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B))
• A58503: Billing and Coding: Echocardiography for Myocardial Perfusion (Palmetto GBA (MAC - Part A, MAC - Part B))

Covered diagnoses (1,839 ICD-10-CM codes)

The diagnoses most often listed as covered in the policy articles above:

Showing 10 of 1,839. The full list, non-covered diagnoses and CSV export are in Caduvo.

What changed for Q9955

• 2005-04-01: Q9955 added to HCPCS Level II
• Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01

Frequently asked questions

What is HCPCS code Q9955?

Q9955 is the HCPCS Level II code for injection, perflexane lipid microspheres, per ml. Short descriptor: "Inj perflexane lip micros,ml".

Does Medicare cover Q9955?

Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.

Which diagnoses support coverage for Q9955?

Medicare policy articles that cite Q9955 list 1,839 covered ICD-10-CM diagnosis codes across 4 articles. The most cited include I21.01 (ST elevation (STEMI) myocardial infarction involving left main coronary artery), I21.02 (ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery), I21.09 (ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wall). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.

Related Q99 codes

• Q9950 — Injection, sulfur hexafluoride lipid microspheres, per ml
• Q9951 — Low osmolar contrast material, 400 or greater mg/ml iodine concentration, per ml
• Q9953 — Injection, iron-based magnetic resonance contrast agent, per ml
• Q9954 — Oral magnetic resonance contrast agent, per 100 ml
• Q9956 — Injection, octafluoropropane microspheres, per ml
• Q9957 — Injection, perflutren lipid microspheres, per ml
• Q9958 — High osmolar contrast material, up to 149 mg/ml iodine concentration, per ml
• Q9959 — High osmolar contrast material, 150-199 mg/ml iodine concentration, per ml
• Q9960 — High osmolar contrast material, 200-249 mg/ml iodine concentration, per ml
• Q9961 — High osmolar contrast material, 250-299 mg/ml iodine concentration, per ml
• Q9962 — High osmolar contrast material, 300-349 mg/ml iodine concentration, per ml
• Q9963 — High osmolar contrast material, 350-399 mg/ml iodine concentration, per ml

Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.

Next steps

• Run a reimbursement report for a device billed under Q9955
• Watch Q9955 for fee, coverage and descriptor changes
• Build a full Medicare revenue model for Q9955

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

All Q codes · HCPCS lookup