S0353 HCPCS code: Treatment planning and care coordination management for cancer, initial treatment
S0353 is the HCPCS Level II code for treatment planning and care coordination management for cancer, initial treatment. Its Medicare coverage code is I (Not payable by Medicare): Medicare does not pay separately under this code; another code applies.
Code details
| Field | Value |
|---|---|
| Section | S codes — Temporary national codes (non-Medicare) |
| Coverage code | I — Not payable by Medicare |
| Pricing indicator | 00 — Not separately priced by Medicare |
| BETOS category | Z2 |
| Added | 2012-04-01 |
| Last action effective | 2012-04-01 |
What changed for S0353
- 2012-04-01: S0353 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code S0353?
S0353 is the HCPCS Level II code for treatment planning and care coordination management for cancer, initial treatment. Short descriptor: "Cancer treatmentplan initial".
Does Medicare cover S0353?
Coverage code I — Not payable by Medicare. Medicare does not pay separately under this code; another code applies.
Related S03 codes
- S0302 — Completed early periodic screening diagnosis and treatment (epsdt) service (list in addition to code for appropriate evaluation and management service)
- S0310 — Hospitalist services (list separately in addition to code for appropriate evaluation and management service)
- S0311 — Comprehensive management and care coordination for advanced illness, per calendar month
- S0315 — Disease management program; initial assessment and initiation of the program
- S0316 — Disease management program, follow-up/reassessment
- S0317 — Disease management program; per diem
- S0320 — Telephone calls by a registered nurse to a disease management program member for monitoring purposes; per month
- S0340 — Lifestyle modification program for management of coronary artery disease, including all supportive services; first quarter / stage
- S0341 — Lifestyle modification program for management of coronary artery disease, including all supportive services; second or third quarter / stage
- S0342 — Lifestyle modification program for management of coronary artery disease, including all supportive services; fourth quarter / stage
- S0354 — Treatment planning and care coordination management for cancer, established patient with a change of regimen
- S0390 — Routine foot care; removal and/or trimming of corns, calluses and/or nails and preventive maintenance in specific medical conditions (e.g., diabetes), per visit
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Next steps
- Run a reimbursement report for a device billed under S0353
- Watch S0353 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for S0353
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.