S3620 HCPCS code: Newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total)
S3620 is the HCPCS Level II code for newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total). Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met.
Code details
| Field | Value |
|---|---|
| Section | S codes — Temporary national codes (non-Medicare) |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 00 — Not separately priced by Medicare |
| BETOS category | Z2 |
| Added | 2001-01-01 |
| Last action effective | 2001-07-01 |
What changed for S3620
- 2001-01-01: S3620 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code S3620?
S3620 is the HCPCS Level II code for newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total). Short descriptor: "Newborn metabolic screening".
Does Medicare cover S3620?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Related S36 codes
- S3600 — Stat laboratory request (situations other than s3601)
- S3601 — Emergency stat laboratory charge for patient who is homebound or residing in a nursing facility
- S3630 — Eosinophil count, blood, direct
- S3645 — Hiv-1 antibody testing of oral mucosal transudate
- S3650 — Saliva test, hormone level; during menopause
- S3652 — Saliva test, hormone level; to assess preterm labor risk
- S3655 — Antisperm antibodies test (immunobead)
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Next steps
- Run a reimbursement report for a device billed under S3620
- Watch S3620 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for S3620
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.