S4991 HCPCS code: Nicotine patches, non-legend
S4991 is the HCPCS Level II code for nicotine patches, non-legend. Its Medicare coverage code is I (Not payable by Medicare): Medicare does not pay separately under this code; another code applies.
Code details
| Field | Value |
|---|---|
| Section | S codes — Temporary national codes (non-Medicare) |
| Coverage code | I — Not payable by Medicare |
| Pricing indicator | 00 — Not separately priced by Medicare |
| BETOS category | Z2 |
| Added | 2002-01-01 |
| Last action effective | 2002-01-01 |
What changed for S4991
- 2002-01-01: S4991 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code S4991?
S4991 is the HCPCS Level II code for nicotine patches, non-legend. Short descriptor: "Nicotine patch nonlegend".
Does Medicare cover S4991?
Coverage code I — Not payable by Medicare. Medicare does not pay separately under this code; another code applies.
Related S49 codes
- S4981 — Insertion of levonorgestrel-releasing intrauterine system
- S4988 — Penile contracture device, manual, greater than 3 lbs traction force
- S4989 — Contraceptive intrauterine device (e.g., progestacert iud), including implants and supplies
- S4990 — Nicotine patches, legend
- S4993 — Contraceptive pills for birth control
- S4995 — Smoking cessation gum
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Next steps
- Run a reimbursement report for a device billed under S4991
- Watch S4991 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for S4991
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.