C79.70: Secondary malignant neoplasm of unspecified adrenal gland
C79.70, secondary malignant neoplasm of unspecified adrenal gland, is listed as a covered diagnosis in 4 Medicare billing and coding articles that apply to 28 HCPCS Level II codes, including Q2043 (Sipuleucel-t, minimum of 50 million autologous cd54+ cells…), G0340 (Image-guided robotic linear accelerator-based stereotactic…), G0339 (Image-guided robotic linear accelerator-based stereotactic…). The articles come from 4 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with C79.70 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| Q2043 | Sipuleucel-t, minimum of 50 million autologous cd54+ cells activated with pap-gm-csf, including leukapheresis and all other preparatory procedures, per infusion | Special coverage instructions apply | — | 1 |
| G0340 | Image-guided robotic linear accelerator-based stereotactic radiosurgery, delivery including collimator changes and custom plugging, fractionated treatment, all lesions, per session, second through fifth sessions, maximum five sessions per course of treatment | Carrier judgment | — | 1 |
| G0339 | Image-guided robotic linear accelerator-based stereotactic radiosurgery, complete course of therapy in one session or first session of fractionated treatment | Carrier judgment | — | 1 |
| G0563 | Stereotactic body radiation therapy, treatment delivery, per fraction to 1 or more lesions, including image guidance and real-time positron emissions-based delivery adjustments to 1 or more lesions, entire course not to exceed 5 fractions | Carrier judgment | — | 1 |
| J8999 | Prescription drug, oral, chemotherapeutic, nos | Special coverage instructions apply | — | 1 |
| Q0512 | Pharmacy supply fee for oral anti-cancer, oral anti-emetic or immunosuppressive drug(s); for a subsequent prescription in a 30-day period | Special coverage instructions apply | — | 1 |
| Q0511 | Pharmacy supply fee for oral anti-cancer, oral anti-emetic or immunosuppressive drug(s); for the first prescription in a 30-day period | Special coverage instructions apply | — | 1 |
| J8530 | Cyclophosphamide; oral, 25 mg | Special coverage instructions apply | — | 1 |
| J8597 | Antiemetic drug, oral, not otherwise specified | Special coverage instructions apply | — | 1 |
| J8610 | Methotrexate; oral, 2.5 mg | Special coverage instructions apply | — | 1 |
| J8498 | Antiemetic drug, rectal/suppository, not otherwise specified | Special coverage instructions apply | — | 1 |
| Q5110 | Injection, filgrastim-aafi, biosimilar, (nivestym), 1 microgram | Special coverage instructions apply | — | 1 |
| Q5125 | Injection, filgrastim-ayow, biosimilar, (releuko), 1 microgram | Carrier judgment | — | 1 |
| Q5101 | Injection, filgrastim-sndz, biosimilar, (zarxio), 1 microgram | Special coverage instructions apply | — | 1 |
| J1442 | Injection, filgrastim (g-csf), excludes biosimilars, 1 microgram | Special coverage instructions apply | — | 1 |
| J1449 | Injection, eflapegrastim-xnst, 0.1 mg | Carrier judgment | — | 1 |
| J1447 | Injection, tbo-filgrastim, 1 microgram | Special coverage instructions apply | — | 1 |
| Q5108 | Injection, pegfilgrastim-jmdb (fulphila), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| Q5111 | Injection, pegfilgrastim-cbqv (udenyca), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| Q5127 | Injection, pegfilgrastim-fpgk (stimufend), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| J2506 | Injection, pegfilgrastim, excludes biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| Q5122 | Injection, pegfilgrastim-apgf (nyvepria), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| Q5130 | Injection, pegfilgrastim-pbbk (fylnetra), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
| J2820 | Injection, sargramostim (gm-csf), 50 mcg | Special coverage instructions apply | — | 1 |
| Q5120 | Injection, pegfilgrastim-bmez (ziextenzo), biosimilar, 0.5 mg | Carrier judgment | — | 1 |
3 more codes are listed. See every code with payment by region in Caduvo.
Medicare policy articles listing C79.70
- A55719: Sipuleucel-T (Provenge®) - Coverage Criteria for Prostate Cancer – Clarification (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B); 1 Level II codes)
- A56874: Billing and Coding: Stereotactic Radiation Therapy: Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT) (Wellpoint Federal (MAC - Part A, MAC - Part B); 3 Level II codes). LCD with the same title: L35076
- A52479: Oral Anticancer Drugs - Policy Article (CGS Administrators, LLC (DME MAC) Noridian Healthcare Solutions, LLC (DME MAC); 8 Level II codes). LCD with the same title: L33826
- A56748: Billing and Coding: White Cell Colony Stimulating Factors (Palmetto GBA (MAC - Part A, MAC - Part B); 16 Level II codes). LCD with the same title: L37176
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Other C79 diagnoses (Secondary malignant neoplasm of other and unspecified sites)
- C79.71 — Secondary malignant neoplasm of right adrenal gland
- C79.72 — Secondary malignant neoplasm of left adrenal gland
- C79.00 — Secondary malignant neoplasm of unspecified kidney and renal pelvis
- C79.01 — Secondary malignant neoplasm of right kidney and renal pelvis
- C79.02 — Secondary malignant neoplasm of left kidney and renal pelvis
- C79.10 — Secondary malignant neoplasm of unspecified urinary organs
- C79.11 — Secondary malignant neoplasm of bladder
- C79.19 — Secondary malignant neoplasm of other urinary organs
- C79.2 — Secondary malignant neoplasm of skin
- C79.31 — Secondary malignant neoplasm of brain
- C79.32 — Secondary malignant neoplasm of cerebral meninges
- C79.40 — Secondary malignant neoplasm of unspecified part of nervous system
- C79.49 — Secondary malignant neoplasm of other parts of nervous system
- C79.51 — Secondary malignant neoplasm of bone
- C79.52 — Secondary malignant neoplasm of bone marrow
- C79.61 — Secondary malignant neoplasm of right ovary
- C79.62 — Secondary malignant neoplasm of left ovary
- C79.63 — Secondary malignant neoplasm of bilateral ovaries
- C79.81 — Secondary malignant neoplasm of breast
- C79.82 — Secondary malignant neoplasm of genital organs
- C79.89 — Secondary malignant neoplasm of other specified sites
- C79.9 — Secondary malignant neoplasm of unspecified site
Frequently asked questions
Does Medicare cover C79.70 (Secondary malignant neoplasm of unspecified adrenal gland)?
Medicare covers items and services, not diagnoses. 4 Medicare billing and coding articles list C79.70 as a covered diagnosis for 28 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 C79.70?
The Level II codes from the policies most specific to this diagnosis are Q2043 (Sipuleucel-t, minimum of 50 million autologous cd54+ cells…, 1 article); G0340 (Image-guided robotic linear accelerator-based stereotactic…, 1 article); G0339 (Image-guided robotic linear accelerator-based stereotactic…, 1 article); G0563 (Stereotactic body radiation therapy, treatment delivery…, 1 article); J8999 (Prescription drug, oral, chemotherapeutic, nos, 1 article). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list C79.70?
A55719 (Sipuleucel-T (Provenge®) - Coverage Criteria for Prostate Cancer – Clarification); A56874 (Billing and Coding: Stereotactic Radiation Therapy: Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT)); A52479 (Oral Anticancer Drugs - Policy Article), and 1 more article.
What is ICD-10-CM code C79.70?
C79.70 is the ICD-10-CM code for secondary malignant neoplasm of unspecified adrenal gland, in category C79 (Secondary malignant neoplasm of other and unspecified sites), chapter 2: Neoplasms.
Next steps
- Run a reimbursement report for a device billed under Q2043
- Watch Q2043 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q2043
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.