D51.0: Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D51.0, vitamin B12 deficiency anemia due to intrinsic factor deficiency, is listed as a covered diagnosis in 9 Medicare billing and coding articles that apply to 4 HCPCS Level II codes, including G0127 (Trimming of dystrophic nails, any number), J3420 (Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg), J3425 (Injection, hydroxocobalamin, intramuscular, 10 mcg). The articles come from 7 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with D51.0 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| G0127 | Trimming of dystrophic nails, any number | Special coverage instructions apply | — | 7 |
| J3420 | Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg | Special coverage instructions apply | — | 1 |
| J3425 | Injection, hydroxocobalamin, intramuscular, 10 mcg | Special coverage instructions apply | — | 1 |
| J0585 | Injection, onabotulinumtoxina, 1 unit | Special coverage instructions apply | — | 1 |
Medicare policy articles listing D51.0
- A57755: Billing and Coding: Vitamin B12 Injections (First Coast Service Options, Inc. (MAC - Part B); 2 Level II codes). LCD with the same title: L33967
- A57759: Billing and Coding: Routine Foot Care and Debridement of Nails (Wellpoint Federal (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33636, L34246
- A57954: Billing and Coding: Routine Foot Care (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
- A57193: Billing and Coding: Routine Foot Care and Debridement of Nails (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33636, L34246
- A56389: Billing and Coding: Upper Gastrointestinal Endoscopy and Visualization (Palmetto GBA (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34434
- A52996: Billing and Coding: Routine Foot Care (Novitas Solutions, Inc. (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
- A56232: Billing and Coding: Foot Care (WPS Insurance Corporation (MAC - Part A, MAC - Part B); 1 Level II codes)
- A57188: Billing and Coding: Routine Foot Care (First Coast Service Options, Inc. (MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
- A56680: Billing and Coding: Routine Foot Care (Palmetto GBA (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Frequently asked questions
Does Medicare cover D51.0 (Vitamin B12 deficiency anemia due to intrinsic factor…)?
Medicare covers items and services, not diagnoses. 9 Medicare billing and coding articles list D51.0 as a covered diagnosis for 4 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 D51.0?
The Level II codes from the policies most specific to this diagnosis are G0127 (Trimming of dystrophic nails, any number, 7 articles); J3420 (Injection, vitamin b-12 cyanocobalamin, up to 1000 mcg, 1 article); J3425 (Injection, hydroxocobalamin, intramuscular, 10 mcg, 1 article); J0585 (Injection, onabotulinumtoxina, 1 unit, 1 article). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list D51.0?
A57755 (Billing and Coding: Vitamin B12 Injections); A57759 (Billing and Coding: Routine Foot Care and Debridement of Nails); A57954 (Billing and Coding: Routine Foot Care), and 6 more articles.
What is ICD-10-CM code D51.0?
D51.0 is the ICD-10-CM code for vitamin B12 deficiency anemia due to intrinsic factor deficiency, in category D51 (Vitamin B12 deficiency anemia), chapter 3: Diseases of the blood and immune mechanism.
Next steps
- Run a reimbursement report for a device billed under G0127
- Watch G0127 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for G0127
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.
Chapter 3: Diseases of the blood and immune mechanism · All diagnoses · HCPCS lookup