Chapter 3: Diseases of the blood and immune mechanism (D50–D89)
135 diagnoses listed as covered by Medicare billing and coding articles for HCPCS Level II codes. All chapters.
D50: Iron deficiency anemia
- D50.0 — Iron deficiency anemia secondary to blood loss (chronic)
D51: Vitamin B12 deficiency anemia
- D51.0 — Vitamin B12 deficiency anemia due to intrinsic factor deficiency
D57: Sickle-cell disorders
- D57.01 — Hb-SS disease with acute chest syndrome
- D57.04 — Hb-SS disease with dactylitis
- D57.211 — Sickle-cell/Hb-C disease with acute chest syndrome
- D57.214 — Sickle-cell/Hb-C disease with dactylitis
- D57.414 — Sickle-cell thalassemia, unspecified, with dactylitis
- D57.434 — Sickle-cell thalassemia beta zero with dactylitis
- D57.454 — Sickle-cell thalassemia beta plus with dactylitis
- D57.811 — Other sickle-cell disorders with acute chest syndrome
- D57.814 — Other sickle-cell disorders with dactylitis
D59: Acquired hemolytic anemia
- D59.0 — Drug-induced autoimmune hemolytic anemia
- D59.10 — Autoimmune hemolytic anemia, unspecified
- D59.11 — Warm autoimmune hemolytic anemia
- D59.12 — Cold autoimmune hemolytic anemia
- D59.13 — Mixed type autoimmune hemolytic anemia
- D59.19 — Other autoimmune hemolytic anemia
- D59.30 — Hemolytic-uremic syndrome, unspecified
- D59.31 — Infection-associated hemolytic-uremic syndrome
- D59.9 — Acquired hemolytic anemia, unspecified
D61: Other aplastic anemias and other bone marrow failure syndromes
- D61.03 — Fanconi anemia
- D61.09 — Other constitutional aplastic anemia
- D61.1 — Drug-induced aplastic anemia
- D61.2 — Aplastic anemia due to other external agents
- D61.3 — Idiopathic aplastic anemia
- D61.810 — Antineoplastic chemotherapy induced pancytopenia
- D61.811 — Other drug-induced pancytopenia
- D61.818 — Other pancytopenia
- D61.82 — Myelophthisis
- D61.89 — Other specified aplastic anemias and other bone marrow failure…
- D61.9 — Aplastic anemia, unspecified
D63: Anemia in chronic diseases classified elsewhere
- D63.1 — Anemia in chronic kidney disease
- D63.8 — Anemia in other chronic diseases classified elsewhere
D64: Other anemias
- D64.81 — Anemia due to antineoplastic chemotherapy
- D64.89 — Other specified anemias
D68: Other coagulation defects
- D68.01 — Von Willebrand disease, type 1
- D68.020 — Von Willebrand disease, type 2A
- D68.021 — Von Willebrand disease, type 2B
- D68.022 — Von Willebrand disease, type 2M
- D68.023 — Von Willebrand disease, type 2N
- D68.03 — Von Willebrand disease, type 3
- D68.04 — Acquired von Willebrand disease
- D68.09 — Other von Willebrand disease
- D68.311 — Acquired hemophilia
- D68.32 — Hemorrhagic disorder due to extrinsic circulating anticoagulants
- D68.4 — Acquired coagulation factor deficiency
D69: Purpura and other hemorrhagic conditions
- D69.3 — Immune thrombocytopenic purpura
- D69.41 — Evans syndrome
- D69.42 — Congenital and hereditary thrombocytopenia purpura
- D69.49 — Other primary thrombocytopenia
- D69.59 — Other secondary thrombocytopenia
D70: Neutropenia
- D70.0 — Congenital agranulocytosis
- D70.1 — Agranulocytosis secondary to cancer chemotherapy
- D70.2 — Other drug-induced agranulocytosis
- D70.3 — Neutropenia due to infection
- D70.4 — Cyclic neutropenia
- D70.8 — Other neutropenia
- D70.9 — Neutropenia, unspecified
D71: Functional disorders of polymorphonuclear neutrophils
- D71.1 — Leukocyte adhesion deficiency
- D71.8 — Other functional disorders of polymorphonuclear neutrophils
- D71.9 — Functional disorders of polymorphonuclear neutrophils, unspecified
D75: Other and unspecified diseases of blood and blood-forming organs
- D75.81 — Myelofibrosis
- D75.84 — Other platelet-activating anti-PF4 disorders
D80: Immunodeficiency with predominantly antibody defects
- D80.0 — Hereditary hypogammaglobulinemia
- D80.1 — Nonfamilial hypogammaglobulinemia
- D80.2 — Selective deficiency of immunoglobulin A [IgA]
- D80.3 — Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4 — Selective deficiency of immunoglobulin M [IgM]
- D80.5 — Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6 — Antibody deficiency with near-normal immunoglobulins or with…
- D80.7 — Transient hypogammaglobulinemia of infancy
- D80.8 — Other immunodeficiencies with predominantly antibody defects
- D80.9 — Immunodeficiency with predominantly antibody defects, unspecified
D81: Combined immunodeficiencies
- D81.0 — Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1 — Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2 — Severe combined immunodeficiency [SCID] with low or normal B-cell…
- D81.30 — Adenosine deaminase deficiency, unspecified
- D81.31 — Severe combined immunodeficiency due to adenosine deaminase deficiency
- D81.32 — Adenosine deaminase 2 deficiency
- D81.39 — Other adenosine deaminase deficiency
- D81.4 — Nezelof's syndrome
- D81.5 — Purine nucleoside phosphorylase [PNP] deficiency
- D81.6 — Major histocompatibility complex class I deficiency
- D81.7 — Major histocompatibility complex class II deficiency
- D81.810 — Biotinidase deficiency
- D81.818 — Other biotin-dependent carboxylase deficiency
- D81.819 — Biotin-dependent carboxylase deficiency, unspecified
- D81.82 — Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
- D81.89 — Other combined immunodeficiencies
- D81.9 — Combined immunodeficiency, unspecified
D82: Immunodeficiency associated with other major defects
- D82.0 — Wiskott-Aldrich syndrome
- D82.1 — Di George's syndrome
- D82.2 — Immunodeficiency with short-limbed stature
- D82.3 — Immunodeficiency following hereditary defective response to…
- D82.4 — Hyperimmunoglobulin E [IgE] syndrome
- D82.8 — Immunodeficiency associated with other specified major defects
D83: Common variable immunodeficiency
- D83.0 — Common variable immunodeficiency with predominant abnormalities of…
- D83.1 — Common variable immunodeficiency with predominant immunoregulatory…
- D83.2 — Common variable immunodeficiency with autoantibodies to B- or T-cells
- D83.8 — Other common variable immunodeficiencies
- D83.9 — Common variable immunodeficiency, unspecified
D84: Other immunodeficiencies
- D84.0 — Lymphocyte function antigen-1 [LFA-1] defect
- D84.1 — Defects in the complement system
- D84.821 — Immunodeficiency due to drugs
- D84.822 — Immunodeficiency due to external causes
- D84.89 — Other immunodeficiencies
- D84.9 — Immunodeficiency, unspecified
D86: Sarcoidosis
- D86.0 — Sarcoidosis of lung
- D86.1 — Sarcoidosis of lymph nodes
- D86.2 — Sarcoidosis of lung with sarcoidosis of lymph nodes
- D86.3 — Sarcoidosis of skin
- D86.81 — Sarcoid meningitis
- D86.82 — Multiple cranial nerve palsies in sarcoidosis
- D86.83 — Sarcoid iridocyclitis
- D86.84 — Sarcoid pyelonephritis
- D86.85 — Sarcoid myocarditis
- D86.86 — Sarcoid arthropathy
- D86.87 — Sarcoid myositis
- D86.89 — Sarcoidosis of other sites
- D86.9 — Sarcoidosis, unspecified
D89: Other disorders involving the immune mechanism, not elsewhere classified
- D89.0 — Polyclonal hypergammaglobulinemia
- D89.1 — Cryoglobulinemia
- D89.3 — Immune reconstitution syndrome
- D89.41 — Monoclonal mast cell activation syndrome
- D89.42 — Idiopathic mast cell activation syndrome
- D89.43 — Secondary mast cell activation
- D89.44 — Hereditary alpha tryptasemia
- D89.49 — Other mast cell activation disorder
- D89.810 — Acute graft-versus-host disease
- D89.811 — Chronic graft-versus-host disease
- D89.812 — Acute on chronic graft-versus-host disease
- D89.813 — Graft-versus-host disease, unspecified
- D89.82 — Autoimmune lymphoproliferative syndrome [ALPS]
- D89.84 — IgG4-related disease
- D89.89 — Other specified disorders involving the immune mechanism, not…