D68.022: Von Willebrand disease, type 2M
D68.022, von Willebrand disease, type 2M, is listed as a covered diagnosis in 3 Medicare billing and coding articles that apply to 45 HCPCS Level II codes, including J7192 (Factor viii (antihemophilic factor, recombinant) per i.u.…), J7189 (Factor viia (antihemophilic factor, recombinant)…), J7195 (Injection, factor ix (antihemophilic factor, recombinant)…). The articles come from 3 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with D68.022 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| J7192 | Factor viii (antihemophilic factor, recombinant) per i.u., not otherwise specified | Special coverage instructions apply | — | 1 |
| J7189 | Factor viia (antihemophilic factor, recombinant), (novoseven rt), 1 microgram | Special coverage instructions apply | — | 1 |
| J7195 | Injection, factor ix (antihemophilic factor, recombinant) per iu, not otherwise specified | Special coverage instructions apply | — | 1 |
| J7201 | Injection, factor ix, fc fusion protein, (recombinant), alprolix, 1 i.u. | Special coverage instructions apply | — | 1 |
| J7187 | Injection, von willebrand factor complex (humate-p), per iu vwf:rco | Special coverage instructions apply | — | 1 |
| J7209 | Injection, factor viii, (antihemophilic factor, recombinant), (nuwiq), 1 i.u. | Carrier judgment | — | 1 |
| J7202 | Injection, factor ix, albumin fusion protein, (recombinant), idelvion, 1 i.u. | Special coverage instructions apply | — | 1 |
| J7190 | Factor viii (antihemophilic factor, human) per i.u. | Special coverage instructions apply | — | 1 |
| J7211 | Injection, factor viii, (antihemophilic factor, recombinant), (kovaltry), 1 i.u. | Carrier judgment | — | 1 |
| J7205 | Injection, factor viii fc fusion protein (recombinant), per iu | Special coverage instructions apply | — | 1 |
| J7179 | Injection, von willebrand factor (recombinant), (vonvendi), 1 i.u. vwf:rco | Special coverage instructions apply | — | 1 |
| J7208 | Injection, factor viii, (antihemophilic factor, recombinant), pegylated-aucl, (jivi), 1 i.u. | Special coverage instructions apply | — | 1 |
| J7207 | Injection, factor viii, (antihemophilic factor, recombinant), pegylated, 1 i.u. | Special coverage instructions apply | — | 1 |
| J7170 | Injection, emicizumab-kxwh, 0.5 mg | Carrier judgment | — | 1 |
| J7185 | Injection, factor viii (antihemophilic factor, recombinant) (xyntha), per i.u. | Carrier judgment | — | 1 |
| J7183 | Injection, von willebrand factor complex (human), wilate, 1 i.u. vwf:rco | Special coverage instructions apply | — | 1 |
| J7186 | Injection, antihemophilic factor viii/von willebrand factor complex (human), per factor viii i.u. | Special coverage instructions apply | — | 1 |
| J7203 | Injection factor ix, (antihemophilic factor, recombinant), glycopegylated, (rebinyn), 1 iu | Special coverage instructions apply | — | 1 |
| J7175 | Injection, factor x, (human), 1 i.u. | Carrier judgment | — | 1 |
| J7180 | Injection, factor xiii (antihemophilic factor, human), 1 i.u. | Carrier judgment | — | 1 |
| J7181 | Injection, factor xiii a-subunit, (recombinant), per iu | Carrier judgment | — | 1 |
| J7182 | Injection, factor viii, (antihemophilic factor, recombinant), (novoeight), per iu | Carrier judgment | — | 1 |
| J7188 | Injection, factor viii (antihemophilic factor, recombinant), (obizur), per i.u. | Special coverage instructions apply | — | 1 |
| J7191 | Factor viii (antihemophilic factor (porcine)), per i.u. | Special coverage instructions apply | — | 1 |
| J7193 | Factor ix (antihemophilic factor, purified, non-recombinant) per i.u. | Special coverage instructions apply | — | 1 |
20 more codes are listed. See every code with payment by region in Caduvo.
Medicare policy articles listing D68.022
- A56065: Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3 (Palmetto GBA (MAC - Part B); 33 Level II codes)
- A59105: Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG) (Wellpoint Federal (MAC - Part A, MAC - Part B); 11 Level II codes). LCD with the same title: L39314
- A57954: Billing and Coding: Routine Foot Care (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L33941, L35138, L37643
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Other D68 diagnoses (Other coagulation defects)
- D68.020 — Von Willebrand disease, type 2A
- D68.021 — Von Willebrand disease, type 2B
- D68.023 — Von Willebrand disease, type 2N
- D68.01 — Von Willebrand disease, type 1
- D68.03 — Von Willebrand disease, type 3
- D68.04 — Acquired von Willebrand disease
- D68.09 — Other von Willebrand disease
- D68.311 — Acquired hemophilia
- D68.32 — Hemorrhagic disorder due to extrinsic circulating anticoagulants
- D68.4 — Acquired coagulation factor deficiency
Frequently asked questions
Does Medicare cover D68.022 (Von Willebrand disease, type 2M)?
Medicare covers items and services, not diagnoses. 3 Medicare billing and coding articles list D68.022 as a covered diagnosis for 45 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 D68.022?
The Level II codes from the policies most specific to this diagnosis are J7192 (Factor viii (antihemophilic factor, recombinant) per i.u.…, 1 article); J7189 (Factor viia (antihemophilic factor, recombinant)…, 1 article); J7195 (Injection, factor ix (antihemophilic factor, recombinant)…, 1 article); J7201 (Injection, factor ix, fc fusion protein, (recombinant)…, 1 article); J7187 (Injection, von willebrand factor complex (humate-p), per…, 1 article). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list D68.022?
A56065 (Billing and Coding: Guidance for Anti-Inhibitor Coagulant Complex (AICC) National Coverage Determination (NCD) 110.3); A59105 (Billing and Coding: Off-Label Use of Intravenous Immune Globulin (IVIG)); A57954 (Billing and Coding: Routine Foot Care).
What is ICD-10-CM code D68.022?
D68.022 is the ICD-10-CM code for von Willebrand disease, type 2M, in category D68 (Other coagulation defects), chapter 3: Diseases of the blood and immune mechanism.
Next steps
- Run a reimbursement report for a device billed under J7192
- Watch J7192 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J7192
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.
Chapter 3: Diseases of the blood and immune mechanism · All diagnoses · HCPCS lookup