D83.1: Common variable immunodeficiency with predominant immunoregulatory T-cell disorders

D83.1, common variable immunodeficiency with predominant immunoregulatory T-cell disorders, is listed as a covered diagnosis in 13 Medicare billing and coding articles that apply to 79 HCPCS Level II codes, including J1569 (Injection, immune globulin, (gammagard liquid/gammagard…), J1552 (Injection, immune globulin (alyglo), 500 mg), J1576 (Injection, immune globulin (panzyga), intravenous…). 25 of these codes have a 2026 DMEPOS fee schedule amount; E0783 pays $9,917.33 to $11,667.45 (NU) depending on the state. The articles come from 7 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with D83.1 as a covered diagnosis

CodeDescriptionMedicare coverageDMEPOS fee 2026 (state range)Articles listing it
J1569Injection, immune globulin, (gammagard liquid/gammagard liquid erc), 500 mgSpecial coverage instructions apply—9
J1552Injection, immune globulin (alyglo), 500 mgCarrier judgment—7
J1576Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—6
J1561Injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—8
J1577Injection, immune globulin (qivigy), 100 mgCarrier judgment—6
J1459Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1557Injection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1556Injection, immune globulin (bivigam), 500 mgCarrier judgment—7
J1568Injection, immune globulin, (octagam), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1566Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mgSpecial coverage instructions apply—7
J1553Injection, immune globulin (yimmugo), 100 mgCarrier judgment—4
J1599Injection, immune globulin, intravenous, non-lyophilized (e.g., liquid), not otherwise specified, 500 mgCarrier judgment—5
J1554Injection, immune globulin (asceniv), 500 mgCarrier judgment—6
J1572Injection, immune globulin, (flebogamma/flebogamma dif), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—4
J2791Injection, rho(d) immune globulin (human), (rhophylac), intramuscular or intravenous, 100 iuSpecial coverage instructions apply—2
J1575Injection, immune globulin/hyaluronidase, (hyqvia), 100 mg immuneglobulinCarrier judgment—4
J1559Injection, immune globulin (hizentra), 100 mgCarrier judgment—3
J1555Injection, immune globulin (cuvitru), 100 mgCarrier judgment—3
J1558Injection, immune globulin (xembify), 100 mgCarrier judgment—3
J1551Injection, immune globulin (cutaquig), 100 mgCarrier judgment—3
J1573Injection, hepatitis b immune globulin (hepagam b), intravenous, 0.5 mlCarrier judgment—2
Q2052Services, supplies and accessories used in the home for the administration of intravenous immune globulin (IVIG)Special coverage instructions apply—1
U00022019-ncov coronavirus, sars-cov-2/2019-ncov (covid-19), any technique, multiple types or subtypes (includes all targets), non-cdcCarrier judgment—4
U0001Cdc 2019 novel coronavirus (2019-ncov) real-time rt-pcr diagnostic panelCarrier judgment—4
J2792Injection, rho d immune globulin, intravenous, human, solvent detergent, 100 iuSpecial coverage instructions apply—1

54 more codes are listed. See every code with payment by region in Caduvo.

Medicare policy articles listing D83.1

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Other D83 diagnoses (Common variable immunodeficiency)

Frequently asked questions

Does Medicare cover D83.1 (Common variable immunodeficiency with predominant…)?

Medicare covers items and services, not diagnoses. 13 Medicare billing and coding articles list D83.1 as a covered diagnosis for 79 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 D83.1?

The Level II codes from the policies most specific to this diagnosis are J1569 (Injection, immune globulin, (gammagard liquid/gammagard…, 9 articles); J1552 (Injection, immune globulin (alyglo), 500 mg, 7 articles); J1576 (Injection, immune globulin (panzyga), intravenous…, 6 articles); J1561 (Injection, immune globulin, (gamunex-c/gammaked)…, 8 articles); J1577 (Injection, immune globulin (qivigy), 100 mg, 6 articles). Code choice depends on the item supplied; check each code's descriptor.

What does Medicare pay for equipment billed with D83.1?

Under the 2026 DMEPOS fee schedule (non-rural state fees): E0783 $9,917.33 to $11,667.45 (NU); E0786 $10,969.75 to $11,380.88 (NU); E0782 $5,200.92 to $6,118.73 (NU); E0785 $572.38 to $673.39 (KF). Medicare pays 80% of the allowed amount after the Part B deductible.

Which Medicare policy articles list D83.1?

A52509 (Intravenous Immune Globulin - Policy Article); A57187 (Billing and Coding: Immune Globulin Intravenous (IVIg)); A56779 (Billing and Coding: Intravenous Immune Globulin), and 10 more articles.

What is ICD-10-CM code D83.1?

D83.1 is the ICD-10-CM code for common variable immunodeficiency with predominant immunoregulatory T-cell disorders, in category D83 (Common variable immunodeficiency), chapter 3: Diseases of the blood and immune mechanism.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 3: Diseases of the blood and immune mechanism · All diagnoses · HCPCS lookup