E52: Niacin deficiency [pellagra]

E52, niacin deficiency [pellagra], is listed as a covered diagnosis in 7 Medicare billing and coding articles that apply to 1 HCPCS Level II code, including G0127 (Trimming of dystrophic nails, any number). The articles come from 7 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with E52 as a covered diagnosis

CodeDescriptionMedicare coverageDMEPOS fee 2026 (state range)Articles listing it
G0127Trimming of dystrophic nails, any numberSpecial coverage instructions apply—7

Medicare policy articles listing E52

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Frequently asked questions

Does Medicare cover E52 (Niacin deficiency [pellagra])?

Medicare covers items and services, not diagnoses. 7 Medicare billing and coding articles list E52 as a covered diagnosis for 1 HCPCS Level II code: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 E52?

The Level II codes from the policies most specific to this diagnosis are G0127 (Trimming of dystrophic nails, any number, 7 articles). Code choice depends on the item supplied; check each code's descriptor.

Which Medicare policy articles list E52?

A57759 (Billing and Coding: Routine Foot Care and Debridement of Nails); A57954 (Billing and Coding: Routine Foot Care); A57193 (Billing and Coding: Routine Foot Care and Debridement of Nails), and 4 more articles.

What is ICD-10-CM code E52?

E52 is the ICD-10-CM code for niacin deficiency [pellagra], in category E52 (Niacin deficiency [pellagra]), chapter 4: Endocrine, nutritional and metabolic diseases.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 4: Endocrine, nutritional and metabolic diseases · All diagnoses · HCPCS lookup