R53.83: Other fatigue
R53.83, other fatigue, is listed as a covered diagnosis in 6 Medicare billing and coding articles that apply to 6 HCPCS Level II codes, including Q9957 (Injection, perflutren lipid microspheres, per ml), Q9956 (Injection, octafluoropropane microspheres, per ml), Q9950 (Injection, sulfur hexafluoride lipid microspheres, per ml). The articles come from 5 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.
HCPCS Level II codes with R53.83 as a covered diagnosis
| Code | Description | Medicare coverage | DMEPOS fee 2026 (state range) | Articles listing it |
|---|---|---|---|---|
| Q9957 | Injection, perflutren lipid microspheres, per ml | Carrier judgment | — | 1 |
| Q9956 | Injection, octafluoropropane microspheres, per ml | Carrier judgment | — | 1 |
| Q9950 | Injection, sulfur hexafluoride lipid microspheres, per ml | Carrier judgment | — | 1 |
| A9700 | Supply of injectable contrast material for use in echocardiography, per study | Special coverage instructions apply | — | 1 |
| Q9955 | Injection, perflexane lipid microspheres, per ml | Carrier judgment | — | 1 |
| G0255 | Current perception threshold/sensory nerve conduction test, (snct) per limb, any nerve | Non-covered by Medicare | Not covered | 5 |
Medicare policy articles listing R53.83
- A58503: Billing and Coding: Echocardiography for Myocardial Perfusion (Palmetto GBA (MAC - Part A, MAC - Part B); 5 Level II codes). LCD with the same title: L38786
- A57307: Billing and Coding: Nerve Conduction Studies and Electromyography (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34594, L34859, L35048, L35081
- A57478: Billing and Coding: Nerve Conduction Studies and Electromyography (WPS Insurance Corporation (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34594, L34859, L35048, L35081
- A54969: Billing and Coding: Nerve Conduction Studies and Electromyography (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34594, L34859, L35048, L35081
- A57668: Billing and Coding: Nerve Conduction Studies and Electromyography (Wellpoint Federal (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34594, L34859, L35048, L35081
- A56619: Billing and Coding: Nerve Conduction Studies and Electromyography (Palmetto GBA (MAC - Part A, MAC - Part B); 1 Level II codes). LCD with the same title: L34594, L34859, L35048, L35081
A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.
Other R53 diagnoses (Malaise and fatigue)
- R53.1 — Weakness
Frequently asked questions
Does Medicare cover R53.83 (Other fatigue)?
Medicare covers items and services, not diagnoses. 6 Medicare billing and coding articles list R53.83 as a covered diagnosis for 6 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.
Which HCPCS codes can be billed with ICD-10 R53.83?
The Level II codes from the policies most specific to this diagnosis are Q9957 (Injection, perflutren lipid microspheres, per ml, 1 article); Q9956 (Injection, octafluoropropane microspheres, per ml, 1 article); Q9950 (Injection, sulfur hexafluoride lipid microspheres, per ml, 1 article); A9700 (Supply of injectable contrast material for use in…, 1 article); Q9955 (Injection, perflexane lipid microspheres, per ml, 1 article). Code choice depends on the item supplied; check each code's descriptor.
Which Medicare policy articles list R53.83?
A58503 (Billing and Coding: Echocardiography for Myocardial Perfusion); A57307 (Billing and Coding: Nerve Conduction Studies and Electromyography); A57478 (Billing and Coding: Nerve Conduction Studies and Electromyography), and 3 more articles.
What is ICD-10-CM code R53.83?
R53.83 is the ICD-10-CM code for other fatigue, in category R53 (Malaise and fatigue), chapter 18: Symptoms, signs and abnormal findings.
Next steps
- Run a reimbursement report for a device billed under Q9957
- Watch Q9957 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q9957
Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.
Chapter 18: Symptoms, signs and abnormal findings · All diagnoses · HCPCS lookup