J1212 HCPCS code: Injection, dmso, dimethyl sulfoxide, 50%, 50 ml
J1212 is the HCPCS Level II code for injection, dmso, dimethyl sulfoxide, 50%, 50 ml. In 2024 Medicare paid an average of $513.89 per service for J1212 across 4,927 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 1 per day on outpatient hospital claims. Medicare volume fell 8% from 2022 to 2024 (5,369 to 4,927 services). In 2024, about 300 clinicians billed Medicare for J1212 for 566 beneficiaries; California, Pennsylvania, Virginia accounted for 76% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 1986-01-01 |
| Last action effective | 2017-01-01 |
Who bills J1212 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 300 |
| Medicare beneficiaries | 566 |
| States with claims | 16 |
| Share of services in top 3 states (California, Pennsylvania, Virginia) | 76% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J1212, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 5,369 | 714 | $575.23 | $455.73 |
| 2023 | 4,703 | 601 | $611.37 | $484.53 |
| 2024 | 4,927 | 566 | $648.49 | $513.89 |
States with the most J1212 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 2,632 | $528.56 |
| Pennsylvania | 571 | $524.43 |
| Virginia | 231 | $537.58 |
| Florida | 175 | $532.38 |
| Massachusetts | 158 | $543.29 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 1 | Prescribing Information |
| practitioner claims | 1 | Prescribing Information |
What changed for J1212
- 1986-01-01: J1212 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J1212?
J1212 is the HCPCS Level II code for injection, dmso, dimethyl sulfoxide, 50%, 50 ml. Short descriptor: "Dimethyl sulfoxide 50% 50 ml".
How much does Medicare pay for J1212?
In 2024, the average Medicare payment was $513.89 per service (average allowed $648.49).
Does Medicare cover J1212?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J1212 can be billed per day?
1 on outpatient hospital claims; 1 on practitioner claims (NCCI medically unlikely edits).
Related J12 codes
- J1200 — Injection, diphenhydramine hcl, up to 50 mg
- J1201 — Injection, cetirizine hydrochloride, 0.5 mg
- J1202 — Miglustat, oral, 65 mg
- J1203 — Injection, cipaglucosidase alfa-atga, 5 mg
- J1205 — Injection, chlorothiazide sodium, per 500 mg
- J1230 — Injection, methadone hcl, up to 10 mg
- J1240 — Injection, dimenhydrinate, up to 50 mg
- J1245 — Injection, dipyridamole, per 10 mg
- J1250 — Injection, dobutamine hydrochloride, per 250 mg
- J1260 — Injection, dolasetron mesylate, 10 mg
- J1265 — Injection, dopamine hcl, 40 mg
- J1267 — Injection, doripenem, 10 mg
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Next steps
- Run a reimbursement report for a device billed under J1212
- Watch J1212 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J1212
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.