J1250 HCPCS code: Injection, dobutamine hydrochloride, per 250 mg

J1250 is the HCPCS Level II code for injection, dobutamine hydrochloride, per 250 mg. In 2024 Medicare paid an average of $6.67 per service for J1250 across 3,818 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 60 per day on DME suppliers. Medicare volume fell 33% from 2022 to 2024 (5,731 to 3,818 services). In 2024, about 663 clinicians billed Medicare for J1250 for 3,442 beneficiaries; California, Georgia, New York accounted for 35% of services.

Code details

Who bills J1250 (2024)

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J1250, 2022–2024

States with the most J1250 services (2024)

NCCI unit limits (MUE)

Medicare policy articles for this code

• A54768: Billing and Coding: Cardiac Blood Pool Imaging (Multiple Gated Acquisition Scanning- MUGA, Ventriculography) When Performed in Conjunction with Cardiotoxic Chemotherapy (Palmetto GBA (MAC - Part A, MAC - Part B))
• A56476: Billing and Coding: Cardiac Radionuclide Imaging (Palmetto GBA (MAC - Part A, MAC - Part B))
• A56494: Billing and Coding: Cardiovascular Nuclear Medicine (CGS Administrators, LLC (MAC - Part A, MAC - Part B))
• A56625: Billing and Coding: Echocardiography (Palmetto GBA (MAC - Part A, MAC - Part B))
• A56781: Billing and Coding: Transthoracic Echocardiography (TTE) (National Government Services, Inc. (MAC - Part A, MAC - Part B))
• A57183: Billing and Coding: Cardiovascular Stress Testing, Including Exercise and/or Pharmacological Stress and Stress Echocardiography (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B))
• A57306: Billing and Coding: Transthoracic Echocardiography (TTE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B))

Covered diagnoses (3,906 ICD-10-CM codes)

The diagnoses most often listed as covered in the policy articles above:

Showing 10 of 3,906. The full list, non-covered diagnoses and CSV export are in Caduvo.

What changed for J1250

• 1996-01-01: J1250 added to HCPCS Level II
• Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01

Frequently asked questions

What is HCPCS code J1250?

J1250 is the HCPCS Level II code for injection, dobutamine hydrochloride, per 250 mg. Short descriptor: "Inj dobutamine hcl/250 mg".

How much does Medicare pay for J1250?

In 2024, the average Medicare payment was $6.67 per service (average allowed $8.47).

Does Medicare cover J1250?

Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.

Which diagnoses support coverage for J1250?

Medicare policy articles that cite J1250 list 3,906 covered ICD-10-CM diagnosis codes across 7 articles. The most cited include I20.1 (Angina pectoris with documented spasm), I20.81 (Angina pectoris with coronary microvascular dysfunction), I20.89 (Other forms of angina pectoris). A listed diagnosis is necessary but not sufficient; the policy's other criteria still apply.

How many units of J1250 can be billed per day?

60 on DME suppliers; 4 on outpatient hospital claims; 2 on practitioner claims (NCCI medically unlikely edits).

Related J12 codes

• J1200 — Injection, diphenhydramine hcl, up to 50 mg
• J1201 — Injection, cetirizine hydrochloride, 0.5 mg
• J1202 — Miglustat, oral, 65 mg
• J1203 — Injection, cipaglucosidase alfa-atga, 5 mg
• J1205 — Injection, chlorothiazide sodium, per 500 mg
• J1212 — Injection, dmso, dimethyl sulfoxide, 50%, 50 ml
• J1230 — Injection, methadone hcl, up to 10 mg
• J1240 — Injection, dimenhydrinate, up to 50 mg
• J1245 — Injection, dipyridamole, per 10 mg
• J1260 — Injection, dolasetron mesylate, 10 mg
• J1265 — Injection, dopamine hcl, 40 mg
• J1267 — Injection, doripenem, 10 mg

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Next steps

• Run a reimbursement report for a device billed under J1250
• Watch J1250 for fee, coverage and descriptor changes
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Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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