J2260 HCPCS code: Injection, milrinone lactate, 5 mg
J2260 is the HCPCS Level II code for injection, milrinone lactate, 5 mg. In 2024 Medicare paid an average of $1.14 per service for J2260 across 1,928,791 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. The NCCI unit limit is 252 per day on DME suppliers. Medicare volume fell 19% from 2022 to 2024 (2,392,717 to 1,928,791 services). In 2024, 265 suppliers billed Medicare for J2260 (purchases), serving 1,663 beneficiaries; New Jersey, Texas, Pennsylvania accounted for 39% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 1986-01-01 |
| Last action effective | 2018-01-01 |
Who bills J2260 (2024)
| Measure | Value |
|---|---|
| Suppliers billing rentals | — |
| Suppliers billing purchases | 265 |
| Referring clinicians | 1,295 |
| Medicare beneficiaries | 1,663 |
| States with claims | 43 |
| Share of services in top 3 states (New Jersey, Texas, Pennsylvania) | 39% |
| Year | Suppliers | Beneficiaries |
|---|---|---|
| 2022 | 330 | 2,052 |
| 2023 | 283 | 1,944 |
| 2024 | 265 | 1,663 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J2260, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 2,392,717 | 2,052 | $1.68 | $1.32 |
| 2023 | 2,193,306 | 1,944 | $1.91 | $1.49 |
| 2024 | 1,928,791 | 1,663 | $1.46 | $1.14 |
States with the most J2260 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| New Jersey | 342,970 | $1.15 |
| Texas | 261,717 | $1.15 |
| Pennsylvania | 141,141 | $1.15 |
| Florida | 126,368 | $1.15 |
| New York | 108,092 | $1.15 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| DME suppliers | 252 | Clinical: Data |
| outpatient hospital claims | 16 | Clinical: Data |
| practitioner claims | 4 | Clinical: Data |
What changed for J2260
- 1986-01-01: J2260 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2260?
J2260 is the HCPCS Level II code for injection, milrinone lactate, 5 mg. Short descriptor: "Inj milrinone lactate / 5 mg".
How much does Medicare pay for J2260?
In 2024, the average Medicare payment was $1.14 per service (average allowed $1.46).
Does Medicare cover J2260?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
How many units of J2260 can be billed per day?
252 on DME suppliers; 16 on outpatient hospital claims; 4 on practitioner claims (NCCI medically unlikely edits).
Related J22 codes
- J2210 — Injection, methylergonovine maleate, up to 0.2 mg
- J2212 — Injection, methylnaltrexone, 0.1 mg
- J2246 — Injection, micafungin in sodium (baxter), not therapeutically equivalent to j2248, 1 mg
- J2247 — Injection, micafungin sodium (par pharm) not thereapeutically equivalent to j2248, 1 mg
- J2248 — Injection, micafungin sodium, 1 mg
- J2249 — Injection, remimazolam, 1 mg
- J2250 — Injection, midazolam hydrochloride, per 1 mg
- J2251 — Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg
- J2252 — Injection, midazolam in 0.8% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg
- J2253 — Injection, midazolam (seizalam), 1 mg
- J2265 — Injection, minocycline hydrochloride, 1 mg
- J2267 — Injection, mirikizumab-mrkz, 1 mg
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under J2260
- Watch J2260 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2260
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.