J2860 HCPCS code: Injection, siltuximab, 10 mg

J2860 is the HCPCS Level II code for injection, siltuximab, 10 mg. In 2024 Medicare paid an average of $115.58 per service for J2860 across 20,250 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. The NCCI unit limit is 170 per day on outpatient hospital claims. Medicare volume fell 10% from 2022 to 2024 (22,476 to 20,250 services). In 2024, about 68 clinicians billed Medicare for J2860 for 27 beneficiaries.

Code details

FieldValue
SectionJ codes — Drugs administered other than oral method
Coverage codeC — Carrier judgment
Pricing indicator51 — Drug or biological (priced per ASP/average sales price rules)
BETOS categoryO1E — Other drugs
Added2016-01-01
Last action effective2016-01-01

Who bills J2860 (2024)

MeasureValue
Clinicians billing (by place of service)68
Medicare beneficiaries27
States with claims0

Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.

Medicare utilization for J2860, 2022–2024

YearServicesBeneficiariesAvg. allowedAvg. paid
202222,47622$127.05$101.35
202323,61623$137.88$110.20
202420,25027$143.05$115.58

NCCI unit limits (MUE)

Claim typeMax units per dayRationale
outpatient hospital claims170Prescribing Information
practitioner claims170Prescribing Information

What changed for J2860

Frequently asked questions

What is HCPCS code J2860?

J2860 is the HCPCS Level II code for injection, siltuximab, 10 mg. Short descriptor: "Injection, siltuximab".

How much does Medicare pay for J2860?

In 2024, the average Medicare payment was $115.58 per service (average allowed $143.05).

Does Medicare cover J2860?

Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.

How many units of J2860 can be billed per day?

170 on outpatient hospital claims; 170 on practitioner claims (NCCI medically unlikely edits).

Related J28 codes

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Next steps

Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.

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