Q4225 HCPCS code: Amniobind or dermabind tl, per square centimeter (add-on, list separately in addition to primary procedure)
Q4225 is the HCPCS Level II code for amniobind or dermabind tl, per square centimeter (add-on, list separately in addition to primary procedure). In 2024 Medicare paid an average of $1,177.13 per service for Q4225 across 16,203 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume rose 2809% from 2022 to 2024 (557 to 16,203 services). In 2024, about 39 clinicians billed Medicare for Q4225 for 103 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 11 — Priced using national relative value units (Physician Fee Schedule) |
| BETOS category | O1E — Other drugs |
| Added | 2022-04-01 |
| Last action effective | 2026-01-01 |
Who bills Q4225 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 39 |
| Medicare beneficiaries | 103 |
| States with claims | 4 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4225, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 557 | 14 | $1,156.45 | $921.40 |
| 2023 | 1,922 | 24 | $1,451.24 | $1,156.27 |
| 2024 | 16,203 | 103 | $1,477.43 | $1,177.13 |
States with the most Q4225 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Michigan | 7,627 | $1,168.19 |
| Florida | 3,669 | $1,172.98 |
| Arkansas | 179 | $1,172.62 |
| Missouri | 108 | $1,176.59 |
What changed for Q4225
- January 2026: Descriptor revised (Was: Amniobind or dermabind tl, per square centimeter)
- 2022-04-01: Q4225 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4225?
Q4225 is the HCPCS Level II code for amniobind or dermabind tl, per square centimeter (add-on, list separately in addition to primary procedure). Short descriptor: "Amnio or derma tl, per sq cm".
How much does Medicare pay for Q4225?
In 2024, the average Medicare payment was $1,177.13 per service (average allowed $1,477.43).
Does Medicare cover Q4225?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
Related Q42 codes
- Q4200 — Skin te, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4201 — Matrion, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4202 — Keroxx (2.5g/cc), 1cc
- Q4203 — Derma-gide, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4204 — Xwrap, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4205 — Membrane graft or membrane wrap, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4206 — Fluid flow or fluid gf, 1 cc
- Q4207 — Carbon life, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4208 — Novafix, per square cenitmeter (add-on, list separately in addition to primary procedure)
- Q4209 — Surgraft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4210 — Axolotl graft or axolotl dualgraft, per square centimeter
- Q4211 — Amnion bio or axobiomembrane, per square centimeter (add-on, list separately in addition to primary procedure)
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Next steps
- Run a reimbursement report for a device billed under Q4225
- Watch Q4225 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4225
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.