Q4229 HCPCS code: Cogenex amniotic membrane, per square centimeter
Q4229 is the HCPCS Level II code for cogenex amniotic membrane, per square centimeter. In 2024 Medicare paid an average of $688.87 per service for Q4229 across 62,994 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume rose 444% from 2022 to 2024 (11,587 to 62,994 services). In 2024, about 346 clinicians billed Medicare for Q4229 for 1,947 beneficiaries; Texas, California, Georgia accounted for 43% of services.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2020-07-01 |
| Last action effective | 2020-07-01 |
Who bills Q4229 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 346 |
| Medicare beneficiaries | 1,947 |
| States with claims | 25 |
| Share of services in top 3 states (Texas, California, Georgia) | 43% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4229, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 11,587 | 313 | $376.93 | $300.37 |
| 2023 | 93,652 | 2,090 | $223.93 | $178.38 |
| 2024 | 62,994 | 1,947 | $864.62 | $688.87 |
States with the most Q4229 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Texas | 12,031 | $711.86 |
| California | 9,682 | $599.75 |
| Georgia | 4,747 | $692.52 |
| South Carolina | 3,912 | $702.96 |
| Massachusetts | 3,886 | $684.78 |
What changed for Q4229
- 2020-07-01: Q4229 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4229?
Q4229 is the HCPCS Level II code for cogenex amniotic membrane, per square centimeter. Short descriptor: "Cogenex amnio memb per sq cm".
How much does Medicare pay for Q4229?
In 2024, the average Medicare payment was $688.87 per service (average allowed $864.62).
Does Medicare cover Q4229?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
Related Q42 codes
- Q4200 — Skin te, per square centimeter
- Q4201 — Matrion, per square centimeter
- Q4202 — Keroxx (2.5g/cc), 1cc
- Q4203 — Derma-gide, per square centimeter
- Q4204 — Xwrap, per square centimeter
- Q4205 — Membrane graft or membrane wrap, per square centimeter
- Q4206 — Fluid flow or fluid gf, 1 cc
- Q4208 — Novafix, per square cenitmeter
- Q4209 — Surgraft, per square centimeter
- Q4210 — Axolotl graft or axolotl dualgraft, per square centimeter
- Q4211 — Amnion bio or axobiomembrane, per square centimeter
- Q4212 — Allogen, per cc
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Next steps
- Run a reimbursement report for a device billed under Q4229
- Watch Q4229 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4229
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.