S2150 HCPCS code: Bone marrow or blood-derived stem cells (peripheral or umbilical), allogeneic or autologous, harvesting, transplantation, and related complications; including: pheresis and cell preparation/storage; marrow ablative therapy; drugs, supplies, hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services; and the number of days of pre-and post-transplant care in the global definition
S2150 is the HCPCS Level II code for bone marrow or blood-derived stem cells (peripheral or umbilical), allogeneic or autologous, harvesting, transplantation, and related complications; including: pheresis and cell preparation/storage; marrow ablative therapy; drugs, supplies, hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services; and the number of days of pre-and post-transplant care in the global definition. Its Medicare coverage code is I (Not payable by Medicare): Medicare does not pay separately under this code; another code applies.
Code details
| Field | Value |
|---|---|
| Section | S codes — Temporary national codes (non-Medicare) |
| Coverage code | I — Not payable by Medicare |
| Pricing indicator | 00 — Not separately priced by Medicare |
| BETOS category | Z2 |
| Added | 2002-01-01 |
| Last action effective | 2004-04-01 |
What changed for S2150
- 2002-01-01: S2150 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code S2150?
S2150 is the HCPCS Level II code for bone marrow or blood-derived stem cells (peripheral or umbilical), allogeneic or autologous, harvesting, transplantation, and related complications; including: pheresis and cell preparation/storage; marrow ablative therapy; drugs, supplies, hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services; and the number of days of pre-and post-transplant care in the global definition. Short descriptor: "Bmt harv/transpl 28d pkg".
Does Medicare cover S2150?
Coverage code I — Not payable by Medicare. Medicare does not pay separately under this code; another code applies.
Related S21 codes
- S2102 — Islet cell tissue transplant from pancreas; allogeneic
- S2103 — Adrenal tissue transplant to brain
- S2107 — Adoptive immunotherapy i.e. development of specific anti-tumor reactivity (e.g., tumor-infiltrating lymphocyte therapy) per course of treatment
- S2112 — Arthroscopy, knee, surgical for harvesting of cartilage (chondrocyte cells)
- S2115 — Osteotomy, periacetabular, with internal fixation
- S2117 — Arthroereisis, subtalar
- S2118 — Metal-on-metal total hip resurfacing, including acetabular and femoral components
- S2120 — Low density lipoprotein (LDL) apheresis using heparin-induced extracorporeal ldl precipitation
- S2140 — Cord blood harvesting for transplantation, allogeneic
- S2142 — Cord blood-derived stem-cell transplantation, allogeneic
- S2152 — Solid organ(s), complete or segmental, single organ or combination of organs; deceased or living donor(s), procurement, transplantation, and related complications; including: drugs; supplies; hospitalization with outpatient follow-up; medical/surgical, diagnostic, emergency, and rehabilitative services, and the number of days of pre- and post-transplant care in the global definition
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Next steps
- Run a reimbursement report for a device billed under S2150
- Watch S2150 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for S2150
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.