S3854 HCPCS code: Gene expression profiling panel for use in the management of breast cancer treatment
S3854 is the HCPCS Level II code for gene expression profiling panel for use in the management of breast cancer treatment. Its Medicare coverage code is I (Not payable by Medicare): Medicare does not pay separately under this code; another code applies.
Code details
| Field | Value |
|---|---|
| Section | S codes — Temporary national codes (non-Medicare) |
| Coverage code | I — Not payable by Medicare |
| Pricing indicator | 00 — Not separately priced by Medicare |
| BETOS category | Z2 |
| Added | 2006-01-01 |
| Last action effective | 2016-07-01 |
What changed for S3854
- 2006-01-01: S3854 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code S3854?
S3854 is the HCPCS Level II code for gene expression profiling panel for use in the management of breast cancer treatment. Short descriptor: "Gene profile panel breast".
Does Medicare cover S3854?
Coverage code I — Not payable by Medicare. Medicare does not pay separately under this code; another code applies.
Related S38 codes
- S3800 — Genetic testing for amyotrophic lateral sclerosis (als)
- S3840 — Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2
- S3841 — Genetic testing for retinoblastoma
- S3842 — Genetic testing for von hippel-lindau disease
- S3844 — Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafness
- S3845 — Genetic testing for alpha-thalassemia
- S3846 — Genetic testing for hemoglobin e beta-thalassemia
- S3849 — Genetic testing for niemann-pick disease
- S3850 — Genetic testing for sickle cell anemia
- S3852 — Dna analysis for apoe epsilon 4 allele for susceptibility to alzheimer's disease
- S3853 — Genetic testing for myotonic muscular dystrophy
- S3855 — Genetic testing for detection of mutations in the presenilin - 1 gene
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Next steps
- Run a reimbursement report for a device billed under S3854
- Watch S3854 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for S3854
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.