C90.00: Multiple myeloma not having achieved remission

C90.00, multiple myeloma not having achieved remission, is listed as a covered diagnosis in 21 Medicare billing and coding articles that apply to 126 HCPCS Level II codes, including J1569 (Injection, immune globulin, (gammagard liquid/gammagard…), J1561 (Injection, immune globulin, (gamunex-c/gammaked)…), J1459 (Injection, immune globulin (privigen), intravenous…). 4 of these codes have a 2026 DMEPOS fee schedule amount; E0783 pays $9,917.33 to $11,667.45 (NU) depending on the state. The articles come from 7 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with C90.00 as a covered diagnosis

CodeDescriptionMedicare coverageDMEPOS fee 2026 (state range)Articles listing it
J1569Injection, immune globulin, (gammagard liquid/gammagard liquid erc), 500 mgSpecial coverage instructions apply—7
J1561Injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—7
J1459Injection, immune globulin (privigen), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1557Injection, immune globulin, (gammaplex), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1556Injection, immune globulin (bivigam), 500 mgCarrier judgment—7
J1568Injection, immune globulin, (octagam), intravenous, non-lyophilized (e.g., liquid), 500 mgCarrier judgment—7
J1566Injection, immune globulin, intravenous, lyophilized (e.g., powder), not otherwise specified, 500 mgSpecial coverage instructions apply—7
J1552Injection, immune globulin (alyglo), 500 mgCarrier judgment—6
J1554Injection, immune globulin (asceniv), 500 mgCarrier judgment—6
J1576Injection, immune globulin (panzyga), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—5
J1577Injection, immune globulin (qivigy), 100 mgCarrier judgment—5
J1572Injection, immune globulin, (flebogamma/flebogamma dif), intravenous, non-lyophilized (e.g., liquid), 500 mgSpecial coverage instructions apply—4
J1553Injection, immune globulin (yimmugo), 100 mgCarrier judgment—3
J1599Injection, immune globulin, intravenous, non-lyophilized (e.g., liquid), not otherwise specified, 500 mgCarrier judgment—4
J1575Injection, immune globulin/hyaluronidase, (hyqvia), 100 mg immuneglobulinCarrier judgment—3
J1559Injection, immune globulin (hizentra), 100 mgCarrier judgment—2
J1555Injection, immune globulin (cuvitru), 100 mgCarrier judgment—2
J1558Injection, immune globulin (xembify), 100 mgCarrier judgment—2
J1551Injection, immune globulin (cutaquig), 100 mgCarrier judgment—2
J0881Injection, darbepoetin alfa, 1 microgram (non-esrd use)Special coverage instructions apply—3
J0885Injection, epoetin alfa, (for non-esrd use), 1000 unitsSpecial coverage instructions apply—3
Q5106Injection, epoetin alfa-epbx, biosimilar, (retacrit) (for non-esrd use), 1000 unitsSpecial coverage instructions apply—3
J0882Injection, darbepoetin alfa, 1 microgram (for esrd on dialysis)Special coverage instructions apply—3
Q5105Injection, epoetin alfa-epbx, biosimilar, (retacrit) (for esrd on dialysis), 100 unitsSpecial coverage instructions apply—3
J0890Injection, peginesatide, 0.1 mg (for esrd on dialysis)Carrier judgment—3

101 more codes are listed. See every code with payment by region in Caduvo.

Medicare policy articles listing C90.00

6 more articles list C90.00.

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Other C90 diagnoses (Multiple myeloma and malignant plasma cell neoplasms)

Frequently asked questions

Does Medicare cover C90.00 (Multiple myeloma not having achieved remission)?

Medicare covers items and services, not diagnoses. 21 Medicare billing and coding articles list C90.00 as a covered diagnosis for 126 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 C90.00?

The Level II codes from the policies most specific to this diagnosis are J1569 (Injection, immune globulin, (gammagard liquid/gammagard…, 7 articles); J1561 (Injection, immune globulin, (gamunex-c/gammaked)…, 7 articles); J1459 (Injection, immune globulin (privigen), intravenous…, 7 articles); J1557 (Injection, immune globulin, (gammaplex), intravenous…, 7 articles); J1556 (Injection, immune globulin (bivigam), 500 mg, 7 articles). Code choice depends on the item supplied; check each code's descriptor.

What does Medicare pay for equipment billed with C90.00?

Under the 2026 DMEPOS fee schedule (non-rural state fees): E0783 $9,917.33 to $11,667.45 (NU); E0786 $10,969.75 to $11,380.88 (NU); E0782 $5,200.92 to $6,118.73 (NU); E0785 $572.38 to $673.39 (KF). Medicare pays 80% of the allowed amount after the Part B deductible.

Which Medicare policy articles list C90.00?

A57187 (Billing and Coding: Immune Globulin Intravenous (IVIg)); A56779 (Billing and Coding: Intravenous Immune Globulin); A56786 (Billing and Coding: Immune Globulin), and 18 more articles.

What is ICD-10-CM code C90.00?

C90.00 is the ICD-10-CM code for multiple myeloma not having achieved remission, in category C90 (Multiple myeloma and malignant plasma cell neoplasms), chapter 2: Neoplasms.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 2: Neoplasms · All diagnoses · HCPCS lookup