J2150 HCPCS code: Injection, mannitol, 25% in 50 ml
J2150 is the HCPCS Level II code for injection, mannitol, 25% in 50 ml. CMS terminated J2150 on 2025-09-30; do not bill it for later dates of service. In 2024 Medicare paid an average of $2.46 per service for J2150 across 5,431 services. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met. Medicare volume fell 42% from 2022 to 2024 (9,436 to 5,431 services). In 2024, about 573 clinicians billed Medicare for J2150 for 1,103 beneficiaries; Illinois, New York, California accounted for 27% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 1986-01-01 |
| Last action effective | 2025-10-01 |
| Terminated | 2025-09-30 |
Who bills J2150 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 573 |
| Medicare beneficiaries | 1,103 |
| States with claims | 22 |
| Share of services in top 3 states (Illinois, New York, California) | 27% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J2150, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 9,436 | 1,703 | $3.40 | $2.69 |
| 2023 | 6,793 | 1,453 | $4.34 | $3.44 |
| 2024 | 5,431 | 1,103 | $3.11 | $2.46 |
States with the most J2150 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Illinois | 496 | $2.39 |
| New York | 438 | $2.53 |
| California | 431 | $2.45 |
| Texas | 424 | $2.39 |
| Arkansas | 374 | $2.52 |
What changed for J2150
- 1986-01-01: J2150 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2150?
J2150 is the HCPCS Level II code for injection, mannitol, 25% in 50 ml. Short descriptor: "Mannitol injection".
How much does Medicare pay for J2150?
In 2024, the average Medicare payment was $2.46 per service (average allowed $3.11).
Does Medicare cover J2150?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Related J21 codes
- J2151 — Injection, mannitol, 250 mg
- J2170 — Injection, mecasermin, 1 mg
- J2175 — Injection, meperidine hydrochloride, per 100 mg
- J2180 — Injection, meperidine and promethazine hcl, up to 50 mg
- J2182 — Injection, mepolizumab, 1 mg
- J2183 — Injection, meropenem (wg critical care), not therapeutically equivalent to j2185, 100 mg
- J2184 — Injection, meropenem (b. braun), not therapeutically equivalent to j2185, 100 mg
- J2185 — Injection, meropenem, 100 mg
- J2186 — Injection, meropenem and vaborbactam, 10mg/10mg (20mg)
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under J2150
- Watch J2150 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2150
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.