J2151 HCPCS code: Injection, mannitol, 250 mg
J2151 is the HCPCS Level II code for injection, mannitol, 250 mg. Its Medicare coverage code is D (Special coverage instructions apply): Medicare covers it when its national or local coverage criteria are met.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | D — Special coverage instructions apply |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2025-10-01 |
| Last action effective | 2025-10-01 |
What changed for J2151
- October 2025: Code appears in this HCPCS release
- 2025-10-01: J2151 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2151?
J2151 is the HCPCS Level II code for injection, mannitol, 250 mg. Short descriptor: "Inj, mannitol, 250 mg".
Does Medicare cover J2151?
Coverage code D — Special coverage instructions apply. Medicare covers it when its national or local coverage criteria are met.
Related J21 codes
- J2150 — Injection, mannitol, 25% in 50 ml
- J2170 — Injection, mecasermin, 1 mg
- J2175 — Injection, meperidine hydrochloride, per 100 mg
- J2180 — Injection, meperidine and promethazine hcl, up to 50 mg
- J2182 — Injection, mepolizumab, 1 mg
- J2183 — Injection, meropenem (wg critical care), not therapeutically equivalent to j2185, 100 mg
- J2184 — Injection, meropenem (b. braun), not therapeutically equivalent to j2185, 100 mg
- J2185 — Injection, meropenem, 100 mg
- J2186 — Injection, meropenem and vaborbactam, 10mg/10mg (20mg)
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Next steps
- Run a reimbursement report for a device billed under J2151
- Watch J2151 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2151
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.