J2315 HCPCS code: Injection, naltrexone, depot form, 1 mg
J2315 is the HCPCS Level II code for injection, naltrexone, depot form, 1 mg. In 2024 Medicare paid an average of $2.24 per service for J2315 across 265,914 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. The NCCI unit limit is 380 per day on outpatient hospital claims. Medicare volume fell 6% from 2022 to 2024 (282,174 to 265,914 services). In 2024, about 318 clinicians billed Medicare for J2315 for 310 beneficiaries; Massachusetts, Wisconsin, Pennsylvania accounted for 54% of services.
Code details
| Field | Value |
|---|---|
| Section | J codes — Drugs administered other than oral method |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2007-01-01 |
| Last action effective | 2007-01-01 |
Who bills J2315 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 318 |
| Medicare beneficiaries | 310 |
| States with claims | 10 |
| Share of services in top 3 states (Massachusetts, Wisconsin, Pennsylvania) | 54% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for J2315, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 282,174 | 344 | $2.94 | $2.33 |
| 2023 | 260,414 | 310 | $3.00 | $2.38 |
| 2024 | 265,914 | 310 | $2.83 | $2.24 |
States with the most J2315 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Massachusetts | 53,320 | $0.70 |
| Wisconsin | 34,201 | $2.71 |
| Pennsylvania | 27,367 | $3.14 |
| Washington | 20,522 | $2.32 |
| Kentucky | 20,143 | $1.94 |
NCCI unit limits (MUE)
| Claim type | Max units per day | Rationale |
|---|---|---|
| outpatient hospital claims | 380 | Prescribing Information |
| practitioner claims | 380 | Prescribing Information |
What changed for J2315
- 2007-01-01: J2315 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code J2315?
J2315 is the HCPCS Level II code for injection, naltrexone, depot form, 1 mg. Short descriptor: "Naltrexone, depot form".
How much does Medicare pay for J2315?
In 2024, the average Medicare payment was $2.24 per service (average allowed $2.83).
Does Medicare cover J2315?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
How many units of J2315 can be billed per day?
380 on outpatient hospital claims; 380 on practitioner claims (NCCI medically unlikely edits).
Related J23 codes
- J2300 — Injection, nalbuphine hydrochloride, per 10 mg
- J2305 — Injection, nitroglycerin, 5 mg
- J2310 — Injection, naloxone hydrochloride, per 1 mg
- J2311 — Injection, naloxone hydrochloride (zimhi), 1 mg
- J2312 — Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg
- J2313 — Injection, naloxone hydrochloride (zimhi), 0.01 mg
- J2320 — Injection, nandrolone decanoate, up to 50 mg
- J2323 — Injection, natalizumab, 1 mg
- J2325 — Injection, nesiritide, 0.1 mg
- J2326 — Injection, nusinersen, 0.1 mg
- J2327 — Injection, risankizumab-rzaa, intravenous, 1 mg
- J2329 — Injection, ublituximab-xiiy, 1mg
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under J2315
- Watch J2315 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for J2315
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.