R23.0: Cyanosis

R23.0, cyanosis, is listed as a covered diagnosis in 4 Medicare billing and coding articles that apply to 40 HCPCS Level II codes, including J2785 (Injection, regadenoson, 0.1 mg), J0461 (Injection, atropine sulfate, 0.01 mg), J0153 (Injection, adenosine, 1 mg (not to be used to report any…). The articles come from 4 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with R23.0 as a covered diagnosis

Code	Description	Medicare coverage	DMEPOS fee 2026 (state range)	Articles listing it
J2785	Injection, regadenoson, 0.1 mg	Carrier judgment	—	2
J0461	Injection, atropine sulfate, 0.01 mg	Special coverage instructions apply	—	2
J0153	Injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds)	Special coverage instructions apply	—	2
Q9957	Injection, perflutren lipid microspheres, per ml	Carrier judgment	—	2
J1250	Injection, dobutamine hydrochloride, per 250 mg	Special coverage instructions apply	—	2
J0280	Injection, aminophyllin, up to 250 mg	Special coverage instructions apply	—	2
J1245	Injection, dipyridamole, per 10 mg	Special coverage instructions apply	—	2
Q9956	Injection, octafluoropropane microspheres, per ml	Carrier judgment	—	2
A9700	Supply of injectable contrast material for use in echocardiography, per study	Special coverage instructions apply	—	2
C8921	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; complete	Special coverage instructions apply	—	2
C8922	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; follow-up or limited study	Special coverage instructions apply	—	2
C8923	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, complete, without spectral or color doppler echocardiography	Special coverage instructions apply	—	2
C8924	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, follow-up or limited study	Special coverage instructions apply	—	2
C8928	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report	Special coverage instructions apply	—	2
C8929	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, complete, with spectral doppler echocardiography, and with color flow doppler echocardiography	Special coverage instructions apply	—	2
C8930	Transthoracic echocardiography, with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report; including performance of continuous electrocardiographic monitoring, with physician supervision	Special coverage instructions apply	—	2
Q9955	Injection, perflexane lipid microspheres, per ml	Carrier judgment	—	2
G0238	Therapeutic procedures to improve respiratory function, other than described by g0237, one on one, face to face, per 15 minutes (includes monitoring)	Carrier judgment	—	1
G0237	Therapeutic procedures to increase strength or endurance of respiratory muscles, face to face, one on one, each 15 minutes (includes monitoring)	Carrier judgment	—	1
G0239	Therapeutic procedures to improve respiratory function or increase strength or endurance of respiratory muscles, two or more individuals (includes monitoring)	Carrier judgment	—	1
J3490	Unclassified drugs	Special coverage instructions apply	—	1
C9399	Unclassified drugs or biologicals	Special coverage instructions apply	—	1
C8900	Magnetic resonance angiography with contrast, abdomen	Special coverage instructions apply	—	1
C8901	Magnetic resonance angiography without contrast, abdomen	Special coverage instructions apply	—	1
C8902	Magnetic resonance angiography without contrast followed by with contrast, abdomen	Special coverage instructions apply	—	1

15 more codes are listed. See every code with payment by region in Caduvo.

Medicare policy articles listing R23.0

A57224: Billing and Coding: Respiratory Care (Noridian Healthcare Solutions, LLC (MAC - Part A, MAC - Part B); 3 Level II codes). LCD with the same title: L34149
A57306: Billing and Coding: Transthoracic Echocardiography (TTE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 19 Level II codes). LCD with the same title: L33577, L34338
A56775: Billing and Coding: Magnetic Resonance Angiography (Palmetto GBA (MAC - Part A, MAC - Part B); 18 Level II codes). LCD with the same title: L34424
A56781: Billing and Coding: Transthoracic Echocardiography (TTE) (Wellpoint Federal (MAC - Part A, MAC - Part B); 17 Level II codes). LCD with the same title: L33577, L34338

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Frequently asked questions

Does Medicare cover R23.0 (Cyanosis)?

Medicare covers items and services, not diagnoses. 4 Medicare billing and coding articles list R23.0 as a covered diagnosis for 40 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 R23.0?

The Level II codes from the policies most specific to this diagnosis are J2785 (Injection, regadenoson, 0.1 mg, 2 articles); J0461 (Injection, atropine sulfate, 0.01 mg, 2 articles); J0153 (Injection, adenosine, 1 mg (not to be used to report any…, 2 articles); Q9957 (Injection, perflutren lipid microspheres, per ml, 2 articles); J1250 (Injection, dobutamine hydrochloride, per 250 mg, 2 articles). Code choice depends on the item supplied; check each code's descriptor.

Which Medicare policy articles list R23.0?

A57224 (Billing and Coding: Respiratory Care); A57306 (Billing and Coding: Transthoracic Echocardiography (TTE)); A56775 (Billing and Coding: Magnetic Resonance Angiography), and 1 more article.

What is ICD-10-CM code R23.0?

R23.0 is the ICD-10-CM code for cyanosis, in category R23 (Other skin changes), chapter 18: Symptoms, signs and abnormal findings.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 18: Symptoms, signs and abnormal findings · All diagnoses · HCPCS lookup