Z52.89: Donor of other specified organs or tissues

Z52.89, donor of other specified organs or tissues, is listed as a covered diagnosis in 5 Medicare billing and coding articles that apply to 22 HCPCS Level II codes, including C8925 (Transesophageal echocardiography (tee) with contrast, or…), C8926 (Transesophageal echocardiography (tee) with contrast, or…), C8927 (Transesophageal echocardiography (tee) with contrast, or…). The articles come from 3 Medicare contractors. A listed diagnosis supports medical necessity only; coverage still depends on the LCD's criteria and on documentation in the medical record.

HCPCS Level II codes with Z52.89 as a covered diagnosis

Code	Description	Medicare coverage	DMEPOS fee 2026 (state range)	Articles listing it
C8925	Transesophageal echocardiography (tee) with contrast, or without contrast followed by with contrast, real time with image documentation (2d) (with or without m-mode recording); including probe placement, image acquisition, interpretation and report	Special coverage instructions apply	—	3
C8926	Transesophageal echocardiography (tee) with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; including probe placement, image acquisition, interpretation and report	Special coverage instructions apply	—	3
C8927	Transesophageal echocardiography (tee) with contrast, or without contrast followed by with contrast, for monitoring purposes, including probe placement, real time 2-dimensional image acquisition and interpretation leading to ongoing (continuous) assessment of (dynamically changing) cardiac pumping function and to therapeutic measures on an immediate time basis	Special coverage instructions apply	—	3
Q9957	Injection, perflutren lipid microspheres, per ml	Carrier judgment	—	3
Q9956	Injection, octafluoropropane microspheres, per ml	Carrier judgment	—	3
Q9955	Injection, perflexane lipid microspheres, per ml	Carrier judgment	—	3
J2785	Injection, regadenoson, 0.1 mg	Carrier judgment	—	2
J0461	Injection, atropine sulfate, 0.01 mg	Special coverage instructions apply	—	2
J0153	Injection, adenosine, 1 mg (not to be used to report any adenosine phosphate compounds)	Special coverage instructions apply	—	2
J1250	Injection, dobutamine hydrochloride, per 250 mg	Special coverage instructions apply	—	2
J0280	Injection, aminophyllin, up to 250 mg	Special coverage instructions apply	—	2
J1245	Injection, dipyridamole, per 10 mg	Special coverage instructions apply	—	2
A9700	Supply of injectable contrast material for use in echocardiography, per study	Special coverage instructions apply	—	2
C8921	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; complete	Special coverage instructions apply	—	2
C8922	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, for congenital cardiac anomalies; follow-up or limited study	Special coverage instructions apply	—	2
C8923	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, complete, without spectral or color doppler echocardiography	Special coverage instructions apply	—	2
C8924	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, follow-up or limited study	Special coverage instructions apply	—	2
C8928	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report	Special coverage instructions apply	—	2
C8929	Transthoracic echocardiography with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, complete, with spectral doppler echocardiography, and with color flow doppler echocardiography	Special coverage instructions apply	—	2
C8930	Transthoracic echocardiography, with contrast, or without contrast followed by with contrast, real-time with image documentation (2d), includes m-mode recording, when performed, during rest and cardiovascular stress test using treadmill, bicycle exercise and/or pharmacologically induced stress, with interpretation and report; including performance of continuous electrocardiographic monitoring, with physician supervision	Special coverage instructions apply	—	2
J3490	Unclassified drugs	Special coverage instructions apply	—	1
C9399	Unclassified drugs or biologicals	Special coverage instructions apply	—	1

Medicare policy articles listing Z52.89

A56809: Billing and Coding: Transesophageal Echocardiography (TEE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 3 Level II codes). LCD with the same title: L33579, L34337, L35016
A56505: Billing and Coding: Transesophageal Echocardiography (TEE) (Novitas Solutions, Inc. (MAC - Part A, MAC - Part B); 6 Level II codes). LCD with the same title: L33579, L34337, L35016
A52868: Billing and Coding: Transesophageal Echocardiography (TEE) (Wellpoint Federal (MAC - Part A, MAC - Part B); 3 Level II codes). LCD with the same title: L33579, L34337, L35016
A57306: Billing and Coding: Transthoracic Echocardiography (TTE) (CGS Administrators, LLC (MAC - Part A, MAC - Part B); 19 Level II codes). LCD with the same title: L33577, L34338
A56781: Billing and Coding: Transthoracic Echocardiography (TTE) (Wellpoint Federal (MAC - Part A, MAC - Part B); 17 Level II codes). LCD with the same title: L33577, L34338

A diagnosis listed as covered in a billing and coding article supports medical necessity for the article's codes; it does not guarantee payment. Coverage depends on the LCD's criteria, the contractor's jurisdiction and documentation in the medical record.

Other Z52 diagnoses (Donors of organs and tissues)

Z52.4 — Kidney donor

Frequently asked questions

Does Medicare cover Z52.89 (Donor of other specified organs or tissues)?

Medicare covers items and services, not diagnoses. 5 Medicare billing and coding articles list Z52.89 as a covered diagnosis for 22 HCPCS Level II codes: the diagnosis can support medical necessity for those codes, but payment still depends on the LCD's coverage criteria and the medical record.

Which HCPCS codes can be billed with ICD-10 Z52.89?

The Level II codes from the policies most specific to this diagnosis are C8925 (Transesophageal echocardiography (tee) with contrast, or…, 3 articles); C8926 (Transesophageal echocardiography (tee) with contrast, or…, 3 articles); C8927 (Transesophageal echocardiography (tee) with contrast, or…, 3 articles); Q9957 (Injection, perflutren lipid microspheres, per ml, 3 articles); Q9956 (Injection, octafluoropropane microspheres, per ml, 3 articles). Code choice depends on the item supplied; check each code's descriptor.

Which Medicare policy articles list Z52.89?

A56809 (Billing and Coding: Transesophageal Echocardiography (TEE)); A56505 (Billing and Coding: Transesophageal Echocardiography (TEE)); A52868 (Billing and Coding: Transesophageal Echocardiography (TEE)), and 2 more articles.

What is ICD-10-CM code Z52.89?

Z52.89 is the ICD-10-CM code for donor of other specified organs or tissues, in category Z52 (Donors of organs and tissues), chapter 22: Factors influencing health status and contact with health services.

Next steps

Sources: CMS Medicare Coverage Database billing and coding articles (covered ICD-10 code lists and HCPCS links); ICD-10-CM FY2026; CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule 2026 (non-rural state fees). Not billing or legal advice.

Chapter 22: Factors influencing health status and contact with health services · All diagnoses · HCPCS lookup