Q4121 HCPCS code: Theraskin, per square centimeter
Q4121 is the HCPCS Level II code for theraskin, per square centimeter. In 2024 Medicare paid an average of $36.27 per service for Q4121 across 36,201 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume fell 69% from 2022 to 2024 (117,462 to 36,201 services). In 2024, about 82 clinicians billed Medicare for Q4121 for 298 beneficiaries; Texas, California, Virginia accounted for 86% of services.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2011-01-01 |
| Last action effective | 2018-01-01 |
Who bills Q4121 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 82 |
| Medicare beneficiaries | 298 |
| States with claims | 5 |
| Share of services in top 3 states (Texas, California, Virginia) | 86% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4121, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 117,462 | 887 | $43.68 | $34.83 |
| 2023 | 63,607 | 584 | $44.31 | $35.28 |
| 2024 | 36,201 | 298 | $45.54 | $36.27 |
States with the most Q4121 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Texas | 15,783 | $36.30 |
| California | 6,010 | $36.25 |
| Virginia | 4,323 | $36.32 |
| Arizona | 2,738 | $36.42 |
| New York | 1,551 | $36.90 |
What changed for Q4121
- 2011-01-01: Q4121 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4121?
Q4121 is the HCPCS Level II code for theraskin, per square centimeter. Short descriptor: "Theraskin".
How much does Medicare pay for Q4121?
In 2024, the average Medicare payment was $36.27 per service (average allowed $45.54).
Does Medicare cover Q4121?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
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Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under Q4121
- Watch Q4121 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4121
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.