Q4133 HCPCS code: Grafix prime, grafixpl prime, stravix and stravixpl, per square centimeter (add-on, list separately in addition to primary procedure)
Q4133 is the HCPCS Level II code for grafix prime, grafixpl prime, stravix and stravixpl, per square centimeter (add-on, list separately in addition to primary procedure). In 2024 Medicare paid an average of $108.16 per service for Q4133 across 57,255 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume fell 57% from 2022 to 2024 (134,112 to 57,255 services). In 2024, about 487 clinicians billed Medicare for Q4133 for 922 beneficiaries; California, Virginia, Arizona accounted for 39% of services.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 11 — Priced using national relative value units (Physician Fee Schedule) |
| BETOS category | O1E — Other drugs |
| Added | 2013-01-01 |
| Last action effective | 2026-01-01 |
Who bills Q4133 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 487 |
| Medicare beneficiaries | 922 |
| States with claims | 23 |
| Share of services in top 3 states (California, Virginia, Arizona) | 39% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4133, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 134,112 | 1,481 | $131.65 | $105.00 |
| 2023 | 80,514 | 1,002 | $132.84 | $105.77 |
| 2024 | 57,255 | 922 | $135.83 | $108.16 |
States with the most Q4133 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 10,930 | $108.02 |
| Virginia | 4,325 | $109.89 |
| Arizona | 4,282 | $108.53 |
| Ohio | 3,529 | $109.48 |
| Pennsylvania | 2,847 | $108.34 |
What changed for Q4133
- January 2026: Descriptor revised (Was: Grafix prime, grafixpl prime, stravix and stravixpl, per square centimeter)
- 2013-01-01: Q4133 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4133?
Q4133 is the HCPCS Level II code for grafix prime, grafixpl prime, stravix and stravixpl, per square centimeter (add-on, list separately in addition to primary procedure). Short descriptor: "Grafix stravix prime pl sqcm".
How much does Medicare pay for Q4133?
In 2024, the average Medicare payment was $108.16 per service (average allowed $135.83).
Does Medicare cover Q4133?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
Related Q41 codes
- Q4100 — Skin substitute, not otherwise specified
- Q4101 — Apligraf, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4102 — Oasis wound matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4103 — Oasis burn matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4104 — Integra bilayer matrix wound dressing (bmwd), per square centimeter (add-on, list separately in addition to primary procedure)
- Q4105 — Integra dermal regeneration template (drt) or integra omnigraft dermal regeneration matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4106 — Dermagraft, per square centimeter
- Q4107 — Graftjacket, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4108 — Integra matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4110 — Primatrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4111 — Gammagraft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4112 — Cymetra, injectable, 1 cc
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under Q4133
- Watch Q4133 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4133
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.