Q4154 HCPCS code: Biovance, per square centimeter
Q4154 is the HCPCS Level II code for biovance, per square centimeter. In 2024 Medicare paid an average of $117.00 per service for Q4154 across 1,577 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume rose 28% from 2022 to 2024 (1,229 to 1,577 services). In 2024, about 31 clinicians billed Medicare for Q4154 for 73 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2015-01-01 |
| Last action effective | 2015-01-01 |
Who bills Q4154 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 31 |
| Medicare beneficiaries | 73 |
| States with claims | 2 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4154, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 1,229 | 32 | $250.90 | $200.20 |
| 2023 | 2,667 | 64 | $138.38 | $110.30 |
| 2024 | 1,577 | 73 | $147.08 | $117.00 |
States with the most Q4154 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Arizona | 895 | $117.22 |
| Mississippi | 158 | $116.93 |
What changed for Q4154
- 2015-01-01: Q4154 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4154?
Q4154 is the HCPCS Level II code for biovance, per square centimeter. Short descriptor: "Biovance 1 square cm".
How much does Medicare pay for Q4154?
In 2024, the average Medicare payment was $117.00 per service (average allowed $147.08).
Does Medicare cover Q4154?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
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- Q4104 — Integra bilayer matrix wound dressing (bmwd), per square centimeter
- Q4105 — Integra dermal regeneration template (drt) or integra omnigraft dermal regeneration matrix, per square centimeter
- Q4106 — Dermagraft, per square centimeter
- Q4107 — Graftjacket, per square centimeter
- Q4108 — Integra matrix, per square centimeter
- Q4110 — Primatrix, per square centimeter
- Q4111 — Gammagraft, per square centimeter
- Q4112 — Cymetra, injectable, 1 cc
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under Q4154
- Watch Q4154 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4154
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.