Q4164 HCPCS code: Helicoll, per square centimeter (add-on, list separately in addition to primary procedure)
Q4164 is the HCPCS Level II code for helicoll, per square centimeter (add-on, list separately in addition to primary procedure). In 2024 Medicare paid an average of $1,212.22 per service for Q4164 across 418,887 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume rose 5236% from 2022 to 2024 (7,850 to 418,887 services). In 2024, about 723 clinicians billed Medicare for Q4164 for 2,430 beneficiaries; California, Florida, Illinois accounted for 66% of services.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 11 — Priced using national relative value units (Physician Fee Schedule) |
| BETOS category | O1E — Other drugs |
| Added | 2016-01-01 |
| Last action effective | 2026-01-01 |
Who bills Q4164 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 723 |
| Medicare beneficiaries | 2,430 |
| States with claims | 28 |
| Share of services in top 3 states (California, Florida, Illinois) | 66% |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4164, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 7,850 | 64 | $710.84 | $566.70 |
| 2023 | 40,073 | 547 | $1,272.24 | $1,013.65 |
| 2024 | 418,887 | 2,430 | $1,521.49 | $1,212.22 |
States with the most Q4164 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| California | 224,009 | $1,228.31 |
| Florida | 27,943 | $1,186.97 |
| Illinois | 19,948 | $1,166.95 |
| New Jersey | 18,323 | $1,207.82 |
| Nevada | 15,897 | $1,227.34 |
What changed for Q4164
- January 2026: Descriptor revised (Was: Helicoll, per square centimeter)
- 2016-01-01: Q4164 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4164?
Q4164 is the HCPCS Level II code for helicoll, per square centimeter (add-on, list separately in addition to primary procedure). Short descriptor: "Helicoll, per square cm".
How much does Medicare pay for Q4164?
In 2024, the average Medicare payment was $1,212.22 per service (average allowed $1,521.49).
Does Medicare cover Q4164?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
Related Q41 codes
- Q4100 — Skin substitute, not otherwise specified
- Q4101 — Apligraf, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4102 — Oasis wound matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4103 — Oasis burn matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4104 — Integra bilayer matrix wound dressing (bmwd), per square centimeter (add-on, list separately in addition to primary procedure)
- Q4105 — Integra dermal regeneration template (drt) or integra omnigraft dermal regeneration matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4106 — Dermagraft, per square centimeter
- Q4107 — Graftjacket, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4108 — Integra matrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4110 — Primatrix, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4111 — Gammagraft, per square centimeter (add-on, list separately in addition to primary procedure)
- Q4112 — Cymetra, injectable, 1 cc
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under Q4164
- Watch Q4164 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4164
Sources: CMS HCPCS Level II release October 2026; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.