Q4199 HCPCS code: Cygnus matrix, per square centimeter
Q4199 is the HCPCS Level II code for cygnus matrix, per square centimeter. In 2024 Medicare paid an average of $246.95 per service for Q4199 across 885 services. Its Medicare coverage code is C (Carrier judgment): Coverage is decided by the Medicare contractor (MAC) case by case. Medicare volume fell 87% from 2022 to 2024 (6,818 to 885 services). In 2024, about 10 clinicians billed Medicare for Q4199 for 28 beneficiaries.
Code details
| Field | Value |
|---|---|
| Section | Q codes — Temporary codes |
| Coverage code | C — Carrier judgment |
| Pricing indicator | 51 — Drug or biological (priced per ASP/average sales price rules) |
| BETOS category | O1E — Other drugs |
| Added | 2022-01-01 |
| Last action effective | 2022-01-01 |
Who bills Q4199 (2024)
| Measure | Value |
|---|---|
| Clinicians billing (by place of service) | 10 |
| Medicare beneficiaries | 28 |
| States with claims | 1 |
Counts only. Supplier and clinician names, contact lists and state-by-state detail are in Caduvo.
Medicare utilization for Q4199, 2022–2024
| Year | Services | Beneficiaries | Avg. allowed | Avg. paid |
|---|---|---|---|---|
| 2022 | 6,818 | 82 | $401.36 | $319.90 |
| 2023 | 6,196 | 122 | $311.40 | $248.05 |
| 2024 | 885 | 28 | $309.95 | $246.95 |
States with the most Q4199 services (2024)
| State | Services | Avg. paid |
|---|---|---|
| Pennsylvania | 409 | $238.85 |
What changed for Q4199
- 2022-01-01: Q4199 added to HCPCS Level II
- Next scheduled CMS quarterly update (HCPCS and DMEPOS fee schedule): 2027-01-01
Frequently asked questions
What is HCPCS code Q4199?
Q4199 is the HCPCS Level II code for cygnus matrix, per square centimeter. Short descriptor: "Cygnus matrix, per sq cm".
How much does Medicare pay for Q4199?
In 2024, the average Medicare payment was $246.95 per service (average allowed $309.95).
Does Medicare cover Q4199?
Coverage code C — Carrier judgment. Coverage is decided by the Medicare contractor (MAC) case by case.
Related Q41 codes
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- Q4101 — Apligraf, per square centimeter
- Q4102 — Oasis wound matrix, per square centimeter
- Q4103 — Oasis burn matrix, per square centimeter
- Q4104 — Integra bilayer matrix wound dressing (bmwd), per square centimeter
- Q4105 — Integra dermal regeneration template (drt) or integra omnigraft dermal regeneration matrix, per square centimeter
- Q4106 — Dermagraft, per square centimeter
- Q4107 — Graftjacket, per square centimeter
- Q4108 — Integra matrix, per square centimeter
- Q4110 — Primatrix, per square centimeter
- Q4111 — Gammagraft, per square centimeter
- Q4112 — Cymetra, injectable, 1 cc
Building a device that would bill under a code like this? Caduvo matches a device description to HCPCS/CPT codes, Medicare coverage and payment, and the FDA pathway in one report.
Next steps
- Run a reimbursement report for a device billed under Q4199
- Watch Q4199 for fee, coverage and descriptor changes
- Build a full Medicare revenue model for Q4199
Sources: CMS HCPCS Level II release October 2025; CMS DMEPOS fee schedule; CMS NCCI MUE tables; CMS Medicare utilization (physician and DME supplier files); CMS Medicare Coverage Database articles. Fees are Medicare allowables, not commercial rates. Not billing or legal advice.